{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:22:20Z","timestamp":1760646140528},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,2,8]],"date-time":"2014-02-08T00:00:00Z","timestamp":1391817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The clinical history of heart failure (HF<\/jats:styled-content>) is usually characterized by frequent hospitalizations for decompensation. Therefore, several markers of subclinical hemodynamic congestion are under investigation for predicting early rehospitalization. In this field, the potential of ultrasound inferior vena cava (IVC<\/jats:styled-content>) assessment has been recently investigated in HF<\/jats:styled-content> but not yet assessed in the different aetiological categories.<\/jats:p><\/jats:sec>Material and methods<\/jats:title>Forty\u2010eight patients admitted for decompensated HF<\/jats:styled-content> (n<\/jats:italic>\u00a0=\u00a025 with ischaemic heart disease [IHD<\/jats:styled-content>] and n<\/jats:italic>\u00a0=\u00a023 non\u2010IHD<\/jats:styled-content>) underwent biochemical examination (including NT<\/jats:styled-content>\u2010proBNP<\/jats:styled-content>), echocardiography and IVC<\/jats:styled-content> assessment by hand\u2010carried ultrasound (HCU<\/jats:styled-content>). During 60\u2010day follow\u2010up after discharge, the re\u2010hospitalization rate for HF<\/jats:styled-content> was recorded to investigate the predictive power of NT<\/jats:styled-content>\u2010proBNP<\/jats:styled-content> and IVC<\/jats:styled-content> assessment among the two study groups.<\/jats:p><\/jats:sec>Results<\/jats:title>IHD<\/jats:styled-content> and non\u2010IHD<\/jats:styled-content> patients with HF<\/jats:styled-content> were similar except for gender distribution.<\/jats:bold> During follow\u2010up, 16\u00b77% of patients were rehospitalized for decompensated HF<\/jats:styled-content>, with higher prevalence in IHD<\/jats:styled-content> group (28% vs. 4\u00b73% P<\/jats:italic>\u00a0=\u00a00\u00b7031). IVC<\/jats:styled-content> assessment at discharge significantly predicted re\u2010admission in the overall population and in IHD<\/jats:styled-content> group, whereas NT<\/jats:styled-content>\u2010proBNP<\/jats:styled-content> failed to predict rehospitalization in IHD<\/jats:styled-content> group. In adjusted hazard ratio, only IVC<\/jats:styled-content> min and the changes of IVC<\/jats:styled-content> from admission significantly predicted re\u2010admission. ROC<\/jats:styled-content> analysis confirmed the change in IVC<\/jats:styled-content> min as the best predictor of rehospitalization in patients with IHD<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This pilot study showed a higher early re\u2010admission rate in patients with HF<\/jats:styled-content> due to IHD<\/jats:styled-content>. In addition, the change in IVC<\/jats:styled-content> min diameter from admission to discharge was the best predictor of re\u2010admission in patients with IHD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.12238","type":"journal-article","created":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T16:00:45Z","timestamp":1389110445000},"page":"341-349","source":"Crossref","is-referenced-by-count":26,"title":["Inferior vena cava parameters predict re\u2010admission in ischaemic heart failure"],"prefix":"10.1111","volume":"44","author":[{"given":"Federico","family":"Carbone","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of Genoa School of Medicine IRCCS Azienda Ospedaliera Universitaria San Martino\u2013IST Istituto Nazionale per la Ricerca sul Cancro Genoa Italy"},{"name":"Division of Cardiology Foundation for Medical Researches Department of Medical Specialties University of Geneva Geneva 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