{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T07:41:42Z","timestamp":1773819702690,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,11,9]],"date-time":"2015-11-09T00:00:00Z","timestamp":1447027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>After several years of study, <jats:styled-content style=\"fixed-case\">CSWT<\/jats:styled-content> has been initially applied to <jats:styled-content style=\"fixed-case\">IHD<\/jats:styled-content> treatment, but the actual effectiveness has never been well evaluated with a meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> EMBASE<\/jats:styled-content>, Science Direct, Cochrane Controlled Trials Register database and Chinese database were searched. The randomized controlled trials, and single\u2010arm and cohort study related to in patients with <jats:styled-content style=\"fixed-case\">IHD<\/jats:styled-content> undergoing <jats:styled-content style=\"fixed-case\">CSWT<\/jats:styled-content> were included and 14 articles were finally analysed. The data related to the study design, patient characteristics and outcomes were extracted. All the selected data were calculated with random\u2010effects models in weighted mean differences, and heterogeneity was carefully evaluated as well.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>(i) Cardiac shock wave therapy improves the angina pectoris symptom (including the decrease of Canadian Cardiovascular Society class [\u22120\u00b786 (\u22121\u00b712, \u22120\u00b765), <jats:italic>P<\/jats:italic> &lt; 0\u00b700001], nitroglycerin dosage (times\/weeks) [\u22120\u00b771 (\u22121\u00b708, \u22120\u00b733), <jats:italic>P<\/jats:italic> = 0\u00b70002] and a increase of Seattle Angina Questionnaire score [5\u00b764 (3\u00b712, 8\u00b715), <jats:italic>P<\/jats:italic> &lt; 0\u00b70001)]); (ii) <jats:styled-content style=\"fixed-case\">CSWT<\/jats:styled-content> leads to a reduce in heart failure (including a reduction of New York Heart Association functional class [\u22120\u00b749 (\u22120\u00b762, \u22120\u00b737), <jats:italic>P<\/jats:italic> &lt; 0\u00b700001], a stable rise in 6\u2010min walking distance [68\u00b738 (39\u00b770, 97\u00b705), <jats:italic>P<\/jats:italic> &lt; 0\u00b700001] and a growth in left ventricular ejection fraction with echocardiography screening [6\u00b773 (4\u00b767,8\u00b780), <jats:italic>P<\/jats:italic> &lt; 0\u00b700001]); (iii) <jats:styled-content style=\"fixed-case\">CSWT<\/jats:styled-content> improves myocardial viability within improving in total score of perfusion imaging [\u22125\u00b719 (\u22128\u00b708, \u22122\u00b730), <jats:italic>P<\/jats:italic> = 0\u00b70004] and total score of metabolism imaging [\u22125\u00b733 (\u22127\u00b777, \u22122\u00b790), <jats:italic>P<\/jats:italic> &lt; 0\u00b70001].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The meta\u2010analysis suggests that <jats:styled-content style=\"fixed-case\">CSWT<\/jats:styled-content> may offer beneficial effects to patients with <jats:styled-content style=\"fixed-case\">IHD<\/jats:styled-content>, although there was significant heterogeneity across the studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.12546","type":"journal-article","created":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T01:23:07Z","timestamp":1444267387000},"page":"1270-1285","source":"Crossref","is-referenced-by-count":16,"title":["Clinical effect of cardiac shock wave therapy on patients with ischaemic heart disease: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"45","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[{"name":"Yunnan Provincial Cardiovascular Institute Kunming China"},{"name":"Department of Cardiology 1st Affiliated Hospital of Kunming Medical University Kunming China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Yunnan Provincial Cardiovascular Institute Kunming China"},{"name":"Department of 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