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In\n                    <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>\n                    the failure of acute inflammation results in the failure to recruit neutrophils to the inflammatory site, as a consequence of which the clearance of bacteria from the tissues is defective. The retained faecal products result in the characteristic chronic granulomatous inflammation and adaptive immune response. Impaired of digestion of bacteria and fungi by\n                    <jats:styled-content style=\"fixed-case\">CGD<\/jats:styled-content>\n                    neutrophils can result in a similar pathological and clinical picture. The neutrophils in\n                    <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>\n                    are normal and their inadequate accumulation at sites of inflammation generally results from diminished secretion of proinflammatory cytokines by macrophages consequent upon disordered vesicle trafficking.\n                  <\/jats:p>","DOI":"10.1111\/eci.12983","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T02:44:21Z","timestamp":1529635461000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["The role of neutrophils in the pathogenesis of Crohn's disease"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7602-9043","authenticated-orcid":false,"given":"Anthony W.","family":"Segal","sequence":"first","affiliation":[{"name":"Division of Medicine University College London London 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