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The frequent rehospitalizations have a negative impact on quality of life of patients with <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>, constituting a substantial cost for patients and the health system. The aim of this review was to look into biochemical, echocardiographic and socioeconomical parameters as predictors of clinical outcomes and rehospitalizations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This narrative review is based on the material searched for and obtained via PubMed from January 2000 up to March 2018. The search terms we used were as follows: \u201celderly, heart failure, cardiovascular\u201d in combination with \u201cbiomarker, echocardiography and hospitalization.\u201d<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This review analyses the potential predictive role of biochemical and echocardiographic and socioeconomical parameters on clinical outcomes (particularly cardiovascular) and hospital readmissions in patients with chronic <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>. We focused on risk stratification of elderly patients with <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>, who constitute a category of frail subjects at higher risk for readmission to hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In elderly subjects with chronic <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>, the risk stratification could benefit of a multiparametric approach combining biochemical, echocardiographic, demographic and socioeconomical parameters, thus ensuring a better quality of life and at the same time a better allocation of financial resources.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.13044","type":"journal-article","created":{"date-parts":[[2018,10,28]],"date-time":"2018-10-28T11:04:41Z","timestamp":1540724681000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Predictors of cardiovascular outcome and 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