{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T22:01:36Z","timestamp":1767909696260,"version":"3.49.0"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with body dysmorphic disorder (BDD) exhibit differential attentional mechanisms compared to healthy subjects. The exact nature of this differentiation is unclear. To this end, EEG (electrophysiological) responses to prepulse inhibition (PPI: reflecting attentional modulation) and prepulse facilitation (PPF: indicating orienting activation) were recorded and analysed. The aim of this study was to compare the respective neural oscillations associated with PPI and PPF in BDD vs healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Event\u2010related EEG oscillations elicited by PPI and PPF (26 and 25 trials, respectively, randomly presented) were explored in a sample of patients with BDD (N\u00a0=\u00a030) vs healthy controls (N\u00a0=\u00a025). The Yale\u2010Brown Obsessive\u2010Compulsive Scale for BDD (BDD\u2010YBOCS), the Body Dysmorphic Disorder Examination, the Dysmorphic Concern Questionnaire (DCQ) and the Brown Assessment of Belief Scale (BABS) were also administered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Analysis of the power spectrum in response to PPI and PPF revealed that the BDD patient group compared to healthy controls exhibited higher theta\u20101 oscillations (potentially indicative of disrupted thalamo\u2010cortical activation) and reduced beta\u20101 oscillations (potentially indicative of reduced top\u2010down\u2010controlled processing during attentional orienting).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings offer novel contributions with regards to the neural mechanisms underlying attention processes in BDD patients, and demonstrate the potential of event\u2010related EEG oscillations as a tool to better understand body dysmorphic disorder.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.13208","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T23:55:30Z","timestamp":1580342130000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Event\u2010related EEG oscillations in body dysmorphic disorder"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4796-3982","authenticated-orcid":false,"given":"Fotini","family":"Kapsali","sequence":"first","affiliation":[{"name":"Psychiatric Hospital of Attica Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioanna","family":"Zioga","sequence":"additional","affiliation":[{"name":"Department of Biological and Experimental Psychology School of Biological and Chemical Sciences Queen Mary University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panos","family":"Papageorgiou","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering University of Patras Patras Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Smyrnis","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry National and Kapodistrian University of Athens Medical School Eginition Hospital Athens Greece"},{"name":"University Mental Health, Neurosciences and Precision Medicine Research Institute \u201cCOSTAS STEFANIS\u201d, (UMHRI) Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George P.","family":"Chrousos","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Metabolism and Diabetes First Department of Pediatrics Medical School Aghia Sofia Children\u2019s Hospital National and Kapodistrian University of Athens Athinon Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charalabos","family":"Papageorgiou","sequence":"additional","affiliation":[{"name":"First Department of Psychiatry National and Kapodistrian University of Athens Medical School Eginition Hospital Athens Greece"},{"name":"University Mental Health, Neurosciences and Precision Medicine Research Institute \u201cCOSTAS STEFANIS\u201d, (UMHRI) Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852916000468"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1975.tb01284.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0511(03)00077-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.07.031"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1910776"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881105048890"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2005.07.032"},{"key":"e_1_2_8_10_1","first-page":"251","volume-title":"Handbook of Cognitive Psychophysiology: Central and Autonomic Nervous System Approaches","author":"Graham FK","year":"1991"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0511(93)90001-O"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2003.10.018"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301601"},{"key":"e_1_2_8_14_1","unstructured":"LarrauriJ SchmajukN.Neurotransmitter Interactions and Cognitive Function Edited by Edward D. 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