{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T04:10:39Z","timestamp":1782101439700,"version":"3.54.5"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201506100001"],"award-info":[{"award-number":["201506100001"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We aimed to assess which sociodemographic factors are associated with current asthma and indicators of lung function in 10\u2010year\u2010old children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed data of 5237 children (Mean age: 9.7, SD: 0.3) from the Generation R Study (2012\u20102016), a population\u2010based cohort study in the Netherlands. Indicators of sociodemographic factors included parental educational level, net household income, financial difficulties, parental employment status and child ethnic background. Current asthma (yes\/no) was defined as ever doctor\u2010diagnosed\u2010asthma combined with wheezing symptoms or asthma\u2010medication use in the past 12\u00a0months. Lung function was measured by spirometry and included forced expiratory volume in 1\u00a0second (FEV<jats:sub>1<\/jats:sub>), forced vital capacity (FVC), FEV<jats:sub>1<\/jats:sub>\/FVC, and forced expiratory flow after exhaling 75% of FVC (FEF<jats:sub>75<\/jats:sub>). Within\u2010study sex\u2010, height\u2010 and age\u2010adjusted lung function measurements\u2019 z\u2010scores were converted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After adjustment for all sociodemographic factors, an independent association was observed between ethnic background with current asthma and lung function. Compared with children with a Dutch background, children with a nonwestern ethnic background had a higher odds of having current asthma (OR: 1.61, 95% CI: 1.02, 2.53), lower FVC z\u2010score (\u22120.25, 95% CI: \u22120.35, \u22120.14), higher FEV<jats:sub>1<\/jats:sub>\/FVC z\u2010score (0.26, 95% CI: 0.14, 0.37) and higher FEF<jats:sub>75%<\/jats:sub> z\u2010score (0.15, 95% CI: 0.04, 0.25).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among 10\u2010year\u2010old children, ethnic background was associated with current asthma and lung function after adjusting for a wide range of sociodemographic factors. No associations were found between socioeconomic status indicators and current asthma. Explanations for these associations such as language barriers, suboptimal care or pathophysiological differences require further investigation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.13277","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T05:50:12Z","timestamp":1591249812000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Sociodemographic factors, current asthma and lung function in an urban child population"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6658-8770","authenticated-orcid":false,"given":"Junwen","family":"Yang\u2010Huang","sequence":"first","affiliation":[{"name":"The Generation R Study Group Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Public Health Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"van Grieken","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelien R.","family":"van Meel","sequence":"additional","affiliation":[{"name":"The Generation R Study Group Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Pediatrics Division of Respiratory Medicine and Allergology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"He","sequence":"additional","affiliation":[{"name":"School of Public Administration Southwestern University of Finance and Economics Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan C.","family":"de Jongste","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Respiratory Medicine and Allergology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liesbeth","family":"Duijts","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Respiratory Medicine and Allergology Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Pediatrics Division of Neonatology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hein","family":"Raat","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.070169"},{"key":"e_1_2_9_3_1","first-page":"548","article-title":"The public health implications of asthma","volume":"83","author":"Bousquet J","year":"2005","journal-title":"Bull World Health Organ"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0b013e3280895d0c"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.26.021304.144528"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2233H"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078266"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1399-3038.2003.00105.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1081\/JAS-120014927"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/JOM.0b013e3181a0363c"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9389570"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00526.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)70195-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.128.2.295"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00114514"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000392"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthplace.2008.02.002"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0352"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh297"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00091612"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-012-9735-1"},{"key":"e_1_2_9_23_1","unstructured":"Statistics Netherlands.Standaard Onderwijsindeling 2003: Voorburg\/Heerlen.2004."},{"key":"e_1_2_9_24_1","unstructured":"Netherlands Bureau for Economic Policy Analysis. Vol. 2017."},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","unstructured":"Statistics Netherlands.Annual report on integration 2012 Summary. Statistics Netherlands.2012.","DOI":"10.1787\/itcs-v2012-4-5-en"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.95.08030483"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13428-018-1081-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2005.08.054"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.05.037"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2011-200333"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/002214650804900202"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200706-867OC"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.080612"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.4.752"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00164109"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/25.3.609"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00156-7"},{"key":"e_1_2_9_39_1","first-page":"508","article-title":"Confounding variables in epidemiologic studies: Basics and beyond","volume":"15","author":"Kamangar F","year":"2012","journal-title":"Arch Iran Med"}],"container-title":["European Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/eci.13277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/eci.13277","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/eci.13277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T21:20:05Z","timestamp":1693948805000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/eci.13277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,11]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/eci.13277"],"URL":"https:\/\/doi.org\/10.1111\/eci.13277","archive":["Portico"],"relation":{},"ISSN":["0014-2972","1365-2362"],"issn-type":[{"value":"0014-2972","type":"print"},{"value":"1365-2362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,11]]},"assertion":[{"value":"2019-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13277"}}