{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:00:42Z","timestamp":1777662042455,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The benefit of implantable cardioverter\u2010defibrillator (ICD) implantation in patients with hemodynamically not tolerated ventricular tachycardia (VT) and midrange reduced to normal ejection fraction (LVEF &gt;35%) is currently unclear. The purpose of this study was to investigate follow\u2010up after hemodynamically not tolerated VT in patients with LVEF &gt;35%. In addition, we aimed to find possible predictive factors to identify who will benefit from ICD implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a retrospective single\u2010centre case series, all patients with hemodynamically not tolerated VT and LVEF &gt;35% that underwent electrophysiological study (EPS) and\/or radiofrequency VT ablation were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two patients (5 women, median age 68\u00a0years) with hemodynamically not tolerated VT and LVEF &gt;35% underwent EPS. VT ablation was performed in thirty\u2010one patients, which was considered successful in twenty\u2010three patients. Nineteen patients had an ICD at discharge while 23 patients were discharged without an ICD. The severity of hemodynamic compromise, LVEF and ablation success played an important role in the decision\u2010making for ICD implantation. Six patients (14.3%) had recurrence of VT, all hemodynamically tolerated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this small case series, patients with hemodynamically not tolerated VT and LVEF &gt;35% had a relatively low recurrence rate and all recurrences were nonfatal. Based on our results, we hypothesize that the severity of hemodynamic compromise, LVEF and ablation success might modify the risk for VA recurrence. A prospective study to determine the prognostic value of these factors in patients with hemodynamically not tolerated VT and LVEF &gt;35% is necessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.13359","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T03:00:41Z","timestamp":1595559641000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Follow\u2010up after hemodynamically not tolerated ventricular tachycardia in patients with midrange reduced to normal ejection fraction: A retrospective single\u2010centre case series"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5942-9675","authenticated-orcid":false,"given":"Sanne A.","family":"Groeneveld","sequence":"first","affiliation":[{"name":"Department of Cardiology University Medical Centre Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart J.","family":"Blom","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Medical Centre Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen F.","family":"van der Heijden","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Medical Centre Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Loh","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Medical Centre Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rutger J.","family":"Hassink","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Medical Centre Utrecht Utrecht The 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