{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:13:26Z","timestamp":1762956806059,"version":"3.41.2"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:00:00Z","timestamp":1649116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Some abnormal electrocardiographic findings were independently associated with increased mortality in patients admitted for COVID\u201019; however, no studies have focussed on the prognosis impact of the interatrial block (IAB) in this clinical setting. The aim of our study was to assess the prevalence and clinical implications of IAB, both partial and advanced, in hospitalized COVID\u201019 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials<\/jats:title><jats:p>We retrospectively evaluated 300 consecutive COVID\u201019 patients (63.22\u00a0\u00b1\u00a015.16\u00a0years; 70% males) admitted to eight Italian Hospitals from February 2020 to April 2020 who\u00a0underwent twelve lead electrocardiographic recording at admission. The study population has been dichotomized into two groups according to the evidence of IAB at admission, both partial and advanced. The differences in terms of ARDS in need of intubation, in\u2010hospital mortality and thromboembolic events (a composite of myocardial infarction, stroke and transient ischaemic attack) have been evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The presence of IAB was noticed in 64 patients (21%). In the adjusted logistic regression model, the partial interatrial block was found to be an independent predictor of ARDS in need of intubation (HR: 1.92; <jats:italic>p<\/jats:italic>: .04) and in\u2010hospital mortality (HR: 2.65; <jats:italic>p<\/jats:italic>: .02); moreover, the advanced interatrial block was an independent predictor of thrombotic events (HR: 7.14; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among COVID\u201019 patients hospitalized in medical wards, the presence of interatrial block is more frequent than in the general population and it might be useful as an early predictor for increased risk of incident thrombotic events, ARDS in need of intubation and in\u2010hospital mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eci.13781","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T08:09:20Z","timestamp":1648454960000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The prognostic role of interatrial block among COVID\u201019 patients hospitalized in medicine wards"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-0360","authenticated-orcid":false,"given":"Vincenzo","family":"Russo","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Translational Medical Sciences Monaldi and Cotugno Hospital University of Campania \u2018Luigi Vanvitelli\u2019  Naples 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