{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T18:40:14Z","timestamp":1782931214479,"version":"3.54.5"},"reference-count":106,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["JR19\/00047"],"award-info":[{"award-number":["JR19\/00047"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PT13\/0002\/0028"],"award-info":[{"award-number":["PT13\/0002\/0028"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RD21\/0012\/0001"],"award-info":[{"award-number":["RD21\/0012\/0001"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RD24\/0013\/0001;PI19\/00702;PI22\/00462;PI16\/00375"],"award-info":[{"award-number":["RD24\/0013\/0001;PI19\/00702;PI22\/00462;PI16\/00375"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J Clin Investigation"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Preeclampsia is a disorder with complex pathophysiology, which underscores the need to study various biomarkers for its early prediction, accurate diagnosis, better understanding of underlying mechanisms and potential links to other diseases. A growing body of research has explored the potential of established and emerging cardiovascular biomarkers in the context of preeclampsia. The overlap in risk factors between preeclampsia and cardiovascular disease, along with findings from numerous epidemiological studies, suggests that cardiovascular biomarkers may play a key role in predicting preeclampsia, assessing its severity and determining the long\u2010term risk of cardiovascular disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To explore the role of cardiovascular biomarkers in the prediction, diagnosis and management of preeclampsia, while investigating their ability to improve insights into disease mechanisms and their connection to long\u2010term cardiovascular risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Discussion<\/jats:title>\n                    <jats:p>This review summarizes findings from existing research on cardiovascular biomarkers in preeclampsia, including studies examining their predictive and diagnostic capabilities, their role in elucidating disease pathophysiology, and their relevance for long\u2010term cardiovascular risk assessment. Furthermore, it highlights emerging cardiovascular biomarkers, outlining their technical limitations and the need for further studies to clarify their utility in routine clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cardiovascular biomarkers are becoming essential for diagnosing, monitoring and predicting outcomes in preeclampsia, enabling early detection and treatment. While some are already in clinical use, emerging biomarkers show promise for more precise and individualized care. Advancing research in this area offers significant potential to improve maternal and fetal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/eci.70123","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:46:09Z","timestamp":1759920369000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cardiovascular biomarkers and preeclampsia: A narrative review"],"prefix":"10.1111","volume":"56","author":[{"given":"Johana","family":"Ullmo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madalina Nicoleta","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Hospital de la Santa Creu i Sant Pau Institut d'Investigaci\u00f3 Biom\u00e8dica Sant Pau (IIB Sant Pau)  Barcelona Spain"},{"name":"Department of Biochemistry and Molecular Biology, Facultat de Medicina Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Cruz\u2010Lemini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"},{"name":"Spanish network in maternal, neonatal, child and developmental health research (RICORS\u2010SAMID) (RD24\/0013\/0001) and Maternal and Child Health Development Network (SAMID, RD21\/0012\/0001) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Garrido\u2010Gimenez","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"},{"name":"Spanish network in maternal, neonatal, child and developmental health research (RICORS\u2010SAMID) (RD24\/0013\/0001) and Maternal and Child Health Development Network (SAMID, RD21\/0012\/0001) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judit","family":"Platero","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6682-0226","authenticated-orcid":false,"given":"\u00c1lvaro","family":"Garc\u00eda\u2010Osuna","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry, Hospital de la Santa Creu i Sant Pau Institut d'Investigaci\u00f3 Biom\u00e8dica Sant Pau (IIB Sant Pau)  Barcelona Spain"},{"name":"Department of Biochemistry and Molecular Biology, Facultat de Medicina Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Garc\u00eda\u2010Manau","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"},{"name":"Spanish network in maternal, neonatal, child and developmental health research (RICORS\u2010SAMID) (RD24\/0013\/0001) and Maternal and Child Health Development Network (SAMID, RD21\/0012\/0001) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8738-207X","authenticated-orcid":false,"given":"Marcel","family":"Twickler","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetology and Metabolic Diseases AZ Monica  Antwerp\/Deurne Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4048-6407","authenticated-orcid":false,"given":"Elisa","family":"Llurba","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Maternal\u2010Fetal Medicine Unit, Hospital de la Santa Creu i Sant Pau Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Women and Perinatal Health Research Group Institut de Recerca (IR SANT PAU)  Barcelona Spain"},{"name":"Spanish network in maternal, neonatal, child and developmental health research (RICORS\u2010SAMID) (RD24\/0013\/0001) and Maternal and Child Health Development Network (SAMID, RD21\/0012\/0001) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-015-0694-y"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.931943"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10113055"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PREGHY.2012.11.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PREGHY.2021.09.008"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.313276"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu018"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)01125-X"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000678"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/EURHEARTJ\/EHAE178"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30977-6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2022.09.003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13540"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-59953-8_2"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2019.03.002"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMOA031884"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050400028816"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414838"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.01787"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.AJOG.2011.07.037"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.015548"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.535294"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.52.9073"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JACC.2011.03.032"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.115.002115"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.15830"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2012.05.004"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2020-001293"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.26911\/thejmch.2024.09.02.06"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/EJHF.592"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.RCE.2016.02.008"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1067\/MOB.2000.105684"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.AJOG.2004.12.006"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2017\/28713.10855"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.934285"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CCA.2016.10.033"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/JCM12020431"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19040"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.5617"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/UOG.27842"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11051327"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2021.07.015"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/EJHF.2848"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41569-020-0381-0"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JACC.2010.02.025"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PREGHY.2012.03.002"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.185264"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1159\/000361016"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JACC.2006.02.056"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/EURHEARTJ\/EHAD191"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2018.11.017"},{"key":"e_1_2_9_54_1","unstructured":"BacmeisterL Go\u00dflingA BuellesbachA.Prediction of preeclampsia using cardiac troponin I.20235\u20136."},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.123.066199"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJCARD.2012.12.039"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03848"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03762"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.04.051"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM-2017-0110"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)64016-0"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/ECI.14225"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.3390\/JPM13071155"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0262330"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PLACENTA.2014.07.003"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PREGHY.2019.02.003"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/IJMS241411295"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1447-0756.2008.00860.X"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/S004040050238"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90317-K"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753944715624853"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1073\/PNAS.94.21.11514"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.3109\/08977194.2011.607137"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1373\/CLINCHEM.2016.255174"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41586-023-06921-9"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1210\/JCEM.85.12.7007"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2002.0881"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CYTO.2016.05.002"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130583"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641955.2018.1524477"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/UOG.22070"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.020302"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/JALM\/JFAC055"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/NRD2660"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JCHF.2016.09.010"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000509"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0024463"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2013.784256"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1286319"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1609934"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EUROX.2021.100140"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.PLACENTA.2018.01.003"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1186\/S12872-023-03696-9"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2018.12.001"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00409"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.01.007"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1182\/BLOOD-2011-07-343566"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI3001"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70213-8"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.EJOGRB.2007.06.014"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.3389\/FMED.2020.00270"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1080\/JMF.12.1.19.27"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70407-6"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/S102380200005"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/PD.1780"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.883780"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10051003"}],"container-title":["European Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/eci.70123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/eci.70123","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/eci.70123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:23:43Z","timestamp":1772990623000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/eci.70123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,8]]},"references-count":106,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/eci.70123"],"URL":"https:\/\/doi.org\/10.1111\/eci.70123","archive":["Portico"],"relation":{},"ISSN":["0014-2972","1365-2362"],"issn-type":[{"value":"0014-2972","type":"print"},{"value":"1365-2362","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,8]]},"assertion":[{"value":"2024-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70123"}}