{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:41Z","timestamp":1787014121686,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T00:00:00Z","timestamp":1379635200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Irish Research Council for Science, Engineering and Technology for an IRCSET EMBARK Fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evolution and Development"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      The venom claws of centipedes, also known as forcipules, represent an evolutionary novelty that must have arisen in the centipede stem species, as they are not found in any other myriapods. The developmental\u2010genetic changes that are involved in the origin of novelties are of considerable interest. It has previously been shown that centipede forcipules have a unique Hox code. However, this is a combinatorial code: no single Hox gene has a forcipule\u2010specific expression. Here, we focus on Wnt genes. Two genes of this family show forcipule\u2010specific expression in the \u201cmodel centipede\u201d\n                      <jats:italic>Strigamia maritima<\/jats:italic>\n                      :\n                      <jats:italic>Wnt7<\/jats:italic>\n                      and\n                      <jats:italic>Wnt11<\/jats:italic>\n                      . For\n                      <jats:italic>Wnt7<\/jats:italic>\n                      , this forcipular expression zone seems to be a new one, which has arisen in evolution subsequently to other expression zones of the same gene. However, for\n                      <jats:italic>Wnt11<\/jats:italic>\n                      , the forcipule\u2010specific expression probably arose by reduction of a more general pattern that originally included most or all of the limbs of an ancestral myriapod. Thus the developmental\u2010genetic basis of the evolutionary change that turned the first pair of walking legs into venom claws is complex, involving different types of change in expression pattern. This sort of complexity is likely to be the case regarding evolutionary changes in morphology in general. Whether the origins of those features that can be considered as novelties are different in terms of their developmental\u2010genetic basis from more routine evolutionary changes remains an open question.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ede.12044","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T07:26:45Z","timestamp":1444721205000},"page":"365-372","source":"Crossref","is-referenced-by-count":9,"title":["Expression patterns of\n                    <i>Wnt<\/i>\n                    genes in the venom claws of centipedes"],"prefix":"10.1111","volume":"15","author":[{"given":"Luke","family":"Hayden","sequence":"first","affiliation":[{"name":"Evolutionary Developmental Biology Laboratory Zoology, School of Natural Sciences, National University of Ireland Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wallace","family":"Arthur","sequence":"additional","affiliation":[{"name":"Evolutionary Developmental Biology Laboratory Zoology, School of Natural Sciences, National University of Ireland Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,9,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.11.2239"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1995.0119"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/41786"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00427-007-0170-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2011.11.006"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-142X.2006.00096.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.22461"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.11.24.3286"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-142X.2004.04016.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.22441"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.10319"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-142X.2011.00527.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asd.2012.02.001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ede.12004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-1878(199802)20:2<116::AID-BIES4>3.0.CO;2-R"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00427-009-0310-z"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21425"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.22448"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.5.1225"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2002.0683"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-142X.2002.02034.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2003.12.021"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2148-10-374"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-142X.2003.03027.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2010.04.024"},{"key":"e_1_2_6_27_1","volume-title":"Evolution After Darwin","author":"Mayr E.","year":"1960"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.20754"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21081"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.es.22.110191.001305"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asd.2010.05.007"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.039651"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2008.47"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1726"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0902804106"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1086\/594532"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21435"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.11.010"}],"container-title":["Evolution &amp; 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