{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T09:47:35Z","timestamp":1771667255749,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,2]],"date-time":"2015-03-02T00:00:00Z","timestamp":1425254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Spontaneous apical closure in non\u2010vital immature teeth has been rarely encountered and outcome of non\u2010surgical endodontic treatment of related teeth associated with periapical lesions has not yet been adequately elucidated. The aim of this article was to report endodontic management of spontaneous apical closure of infected untreated immature teeth with periapical lesions and to review previously proposed mechanisms for the development of spontaneous hard tissue barrier. Three patients were referred at different time intervals to the endodontic clinic for treatment of their maxillary anterior incisors with acute or chronic apical periodontitis<jats:bold>.<\/jats:bold> Dental histories indicated that related teeth had been subjected to trauma approximately 12\u201318\u00a0years previously. Radiographically, the involved teeth exhibited incomplete root formation with spontaneous apical closure and were associated with an apical radiolucency. After biomechanical preparation, calcium hydroxide paste was applied and was changed once or twice within 3\u00a0months. All canals were then filled with gutta\u2010percha and <jats:styled-content style=\"fixed-case\">AH<\/jats:styled-content> Plus and the follow\u2010up period was 16\u201350\u00a0months; both clinical and radiographic examinations revealed adequate function, the absence of clinical symptoms and significant healing of the periapical radiolucency.<\/jats:p>","DOI":"10.1111\/edt.12164","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T00:34:50Z","timestamp":1425342890000},"page":"324-327","source":"Crossref","is-referenced-by-count":6,"title":["Endodontic management of immature teeth with spontaneous apical closure and periapical lesions: case series and review of the literature"],"prefix":"10.1111","volume":"31","author":[{"given":"Mehmet Kemal","family":"\u00c7al\u0131\u015fkan","sequence":"first","affiliation":[{"name":"Department of Endodontology School of Dentistry Ege University Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Emin","family":"Kaval","sequence":"additional","affiliation":[{"name":"Department of Endodontology School of Dentistry Ege University Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,2]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1985.tb00560.x"},{"key":"e_1_2_4_3_1","first-page":"589","article-title":"Apexification: a review of the literature","volume":"21","author":"Morse DR","year":"1990","journal-title":"Quint Int"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2004.00284.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(70)90474-3"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.09.014"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2005.00289.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01415.x"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2007.01214.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.09.009"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(70)90371-3"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(73)90076-5"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(73)90011-X"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(77)80109-X"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(75)90405-3"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(86)80025-5"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(89)80030-5"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(89)80201-8"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200004000-00015"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2008.00677.x"},{"key":"e_1_2_4_21_1","first-page":"31","article-title":"Spontaneous apical closure in a traumatized immature tooth: a case report","volume":"2","author":"Borges BCD","year":"2010","journal-title":"Perspect Oral Sci"},{"key":"e_1_2_4_22_1","first-page":"355","article-title":"Follow\u2010up study of permanent incisors enamel\u2010dentin fractures after acute trauma","volume":"89","author":"Ravn JJ","year":"1981","journal-title":"Scan J Dent Res"},{"key":"e_1_2_4_23_1","first-page":"347","article-title":"Microorganisms from necrotic pulp of traumatized teeth","volume":"25","author":"Bergenholtz G","year":"1974","journal-title":"Odontol Revy J"},{"key":"e_1_2_4_24_1","first-page":"475","article-title":"Influence on periapical tissues of indigenous oral bacteria and necrotic pulp tissue in monkey","volume":"89","author":"M\u00f6ller AJR","year":"1981","journal-title":"Scan J Dent Res"},{"key":"e_1_2_4_25_1","first-page":"45","article-title":"Replantation of 400 avulsed permanent incisors","volume":"8","author":"Andreasen JO","year":"1992","journal-title":"Endod Dent Traumatol"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1988.tb00313.x"},{"key":"e_1_2_4_27_1","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0011-8532(22)02369-2","article-title":"Effect of trauma to the developing permanent dentition","volume":"26","author":"Torneck CD","year":"1982","journal-title":"Dent Clin North Am"}],"container-title":["Dental Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fedt.12164","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/edt.12164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:45:57Z","timestamp":1696261557000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/edt.12164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,2]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/edt.12164"],"URL":"https:\/\/doi.org\/10.1111\/edt.12164","archive":["Portico"],"relation":{},"ISSN":["1600-4469","1600-9657"],"issn-type":[{"value":"1600-4469","type":"print"},{"value":"1600-9657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,2]]}}}