{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T10:14:24Z","timestamp":1789208064033,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T00:00:00Z","timestamp":1440979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Systemic antibiotic therapy (<jats:styled-content style=\"fixed-case\">SAT<\/jats:styled-content>) has usually been recommended after tooth replantation, but its actual value has been questioned. As there are no reports in the literature about its influence on tooth replantation, the aim of this study was to evaluate the influence of systemic administration of antibiotics (amoxicillin and tetracycline) at the different phases of the repair process (7, 15, 30\u00a0days) in delayed rat tooth replantation. Ninety Wistar rats (<jats:italic>Rattus norvegicus albinus<\/jats:italic>) had their maxillary right incisors extracted and bench\u2010dried for 60\u00a0min. The dental papilla, enamel organ, pulp tissue, and root surface\u2010adhered periodontal ligament were removed, and the teeth were replanted. The animals received no antibiotics (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) or were medicated systemically with amoxicillin (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) and tetracycline (<jats:italic>n<\/jats:italic>\u00a0=\u00a030), and were euthanized after 7, 15, and 30\u00a0days. Regardless of the evaluation period, the acute inflammatory infiltrate was less intense and root resorption presented smaller extent and depth in the group treated with amoxicillin. The results suggest that <jats:styled-content style=\"fixed-case\">SAT<\/jats:styled-content> has a positive influence on the repair process in delayed tooth replantation and that amoxicillin is an excellent treatment option.<\/jats:p>","DOI":"10.1111\/edt.12207","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T17:30:15Z","timestamp":1441215015000},"page":"448-456","source":"Crossref","is-referenced-by-count":9,"title":["Delayed tooth replantation in rats: effect of systemic antibiotic therapy with amoxicillin and tetracycline"],"prefix":"10.1111","volume":"31","author":[{"given":"Weglis Dyanne","family":"de Souza Gomes","sequence":"first","affiliation":[{"name":"Department of Surgery and Integrated Clinics School of Dentistry of Ara\u00e7atuba UNESP \u2013 Univ Estadual Paulista Ara\u00e7atuba SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Antoniali","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Surgery and Integrated Clinics School of Dentistry of Ara\u00e7atuba UNESP \u2013 Univ Estadual Paulista Ara\u00e7atuba SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moriel Evangelista","family":"Melo","sequence":"additional","affiliation":[{"name":"Department of Surgery and Integrated Clinics School of Dentistry of Ara\u00e7atuba UNESP \u2013 Univ Estadual Paulista Ara\u00e7atuba SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Ferreira","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Surgery and Integrated Clinics School of Dentistry of Ara\u00e7atuba UNESP \u2013 Univ Estadual Paulista Ara\u00e7atuba SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melyna Marques","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Department of Surgery and Integrated 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