{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:23:32Z","timestamp":1790169812804,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T00:00:00Z","timestamp":1480032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The search for effective protocols to reduce the incidence of root resorption and allow periodontal ligament repair is still challenging, given the unpredictable outcome of late tooth replantation. The aim of this study was to assess the effects of both high\u2010power diode laser irradiation (<jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>) and basic fibroblast growth factor (<jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content>) on the periodontal healing of replanted teeth after extended extra\u2010oral dry time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Maxillary incisors of 50 male rats were extracted and assigned to three experimental and two control groups (<jats:italic>n<\/jats:italic> = 10). <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>: root surfaces treated with <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content> (810 nm, continuous mode, 1.0 W, 30 s), <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content>: topical application of <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content> gel to the root surface and in the alveolar wound, <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content>:<jats:styled-content style=\"fixed-case\"> DL<\/jats:styled-content> and topical application of <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content> gel, C+: no treatment after extraction and immediate replantation and C\u2212: no treatment after extraction and replantation after 60 min. In the experimental groups, the specimens were kept dry for 60 min, the pulps were removed and the canals were filled with calcium hydroxide paste prior to tooth replantation. The animals were euthanized after 60 days. The specimens were processed for radiographic, histological and immunohistochemical analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The radiographic analysis showed fewer resorptive areas in <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content> (<jats:italic>P<\/jats:italic> &lt; 0.05). The histological and immunohistochemical analyses showed that the <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content> group had lower mean values of ankylosis, replacement and inflammatory resorption when compared to C\u2212, not differing statistically from C+. <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content> + <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content> produced significantly more collagen fibers (type I and type <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>) than C\u2212, not differing from C+ in the case of type I fibers (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>, with or without <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content>, reduced the occurrence of external root resorption and ankylosis. Periodontal healing was favored and some fiber reinsertion occurred only when <jats:styled-content style=\"fixed-case\">FGF<\/jats:styled-content> was used.<\/jats:p><\/jats:sec>","DOI":"10.1111\/edt.12308","type":"journal-article","created":{"date-parts":[[2016,10,17]],"date-time":"2016-10-17T05:27:02Z","timestamp":1476682022000},"page":"91-99","source":"Crossref","is-referenced-by-count":17,"title":["Effects of diode laser irradiation and fibroblast growth factor on periodontal healing of replanted teeth after extended extra\u2010oral dry time"],"prefix":"10.1111","volume":"33","author":[{"given":"Erica dos Santos","family":"Carvalho","sequence":"first","affiliation":[{"name":"Division of Endodontics Department of Dentistry Federal University of Bahia Salvador Bahia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rog\u00e9rio Hadid","family":"Rosa","sequence":"additional","affiliation":[{"name":"Department of Dentistry University of Taubate Taubate Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1via de Moura","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Dentistry University of Taubate Taubate Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Lia","family":"Anbinder","sequence":"additional","affiliation":[{"name":"Department of Bioscience and Oral Diagnosis Institute of Science and Technology of Sao Jose dos Campos Universidade Estadual Paulista Sao Jose dos Campos Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Mello","sequence":"additional","affiliation":[{"name":"Division of Endodontics Department of Dental Clinical Sciences Dalhousie University Halifax NS Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Marcia","family":"Habitante","sequence":"additional","affiliation":[{"name":"Department of Dentistry University of Taubate Taubate Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise Pontes","family":"Raldi","sequence":"additional","affiliation":[{"name":"Department of Dentistry University of Taubate Taubate Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2008.00696.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01003.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2012.01125.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01108.x"},{"key":"e_1_2_8_6_1","first-page":"137","article-title":"Permanent tooth replantation following avulsion: using a decision tree to achieve the best outcome","volume":"31","author":"Mclntyre JD","year":"2009","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2013.10.009"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00318-4"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2006.00417.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2008.00667.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2010.00946.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/104454704773660912"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02120.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.10.1312"},{"key":"e_1_2_8_15_1","first-page":"101","article-title":"Interaction between high\u2010power diode laser and dental root surface. 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