{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T18:55:35Z","timestamp":1766516135905,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,2,3]],"date-time":"2019-02-03T00:00:00Z","timestamp":1549152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/Aim<\/jats:title><jats:p>The literature on the pathogenesis of extrusive dental luxation has been focused on periodontal tissue responses, with little attention given to the pulp. The aim of this study was to evaluate the response of dental pulp of teeth following extrusive luxation in a rat model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>The maxillary right central incisors of 30 rats were extrusively luxated and repositioned after 5\u00a0minutes. The animals were euthanized after 7, 15, and 30\u00a0days to provide three groups: I, <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, respectively (n\u00a0=\u00a010). Histological sections were stained with H and E for histomorphometric analysis of the odontoblast layer, reparative dentin deposition, Hertwig's epithelial root sheath, pulp necrosis, and periapical inflammatory infiltrate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In most cases, new vascular formation occured in association with reparative dentin deposition on the root walls and within the pulp. In some cases, dentin deposition occupied the entire pulp space over time, with no other types of non\u2010odontogenic hard tissues being observed. Pulp necrosis with the presence of periapical inflammatory infiltrate was also observed in a few cases. No statistical differences were observed among the studied groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Following extrusive luxation, calcific metamorphosis of the pulp is very likely to occur.<\/jats:p><\/jats:sec>","DOI":"10.1111\/edt.12456","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T14:00:33Z","timestamp":1543327233000},"page":"87-94","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Calcific metamorphosis of pulp after extrusive luxation"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4988-2783","authenticated-orcid":false,"given":"Alfredo Franco","family":"Queiroz","sequence":"first","affiliation":[{"name":"Dentistry Department Universidade Estadual de Maring\u00e1  Maring\u00e1 PR Brazil"},{"name":"Surgery and Integrated Clinics Faculdade de Odontologia de Ara\u00e7atuba Universidade Estadual Paulista  Ara\u00e7atuba SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirian Marubayashi","family":"Hidalgo","sequence":"additional","affiliation":[{"name":"Dentistry Department Universidade Estadual de Maring\u00e1  Maring\u00e1 PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Consolaro","sequence":"additional","affiliation":[{"name":"Pathology Department Faculdade de Odontologia de Bauru Universidade de S\u00e3o Paulo  Bauru SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f4nia Regina","family":"Panzarini","sequence":"additional","affiliation":[{"name":"Surgery and Integrated Clinics Faculdade de Odontologia de Ara\u00e7atuba Universidade Estadual Paulista  Ara\u00e7atuba SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alline Batistussi","family":"Fran\u00e7a","sequence":"additional","affiliation":[{"name":"Surgery and Integrated Clinics 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