{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:58:29Z","timestamp":1775890709817,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T00:00:00Z","timestamp":1374624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the predictors of a significant decrease or cessation of substance use (<jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content>) in a treated epidemiological cohort of first\u2010episode psychosis (<jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content>) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Participants were <jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content> patients of the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>arly <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>sychosis <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>revention and <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ntervention <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>entre in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia. Patients' medical files were reviewed using a standardized file audit. Data on 432 patients with <jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content> and baseline co\u2010morbid substance use disorder (<jats:styled-content style=\"fixed-case\">SUD<\/jats:styled-content>) were available for analysis. Predictors of reduction\/cessation of <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content> at follow up were examined using logistic regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In univariate analyses, a reduction\/cessation of <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content> was predicted by baseline measures reflecting higher education, employment, accommodation with others, cannabis use disorder (<jats:styled-content style=\"fixed-case\">CUD<\/jats:styled-content>) only (rather than poly\u2010SUDs), better global functioning and better premorbid social and occupational functioning, later age at onset of psychosis, and a diagnosis of non\u2010affective psychosis. In multivariate analysis, <jats:styled-content style=\"fixed-case\">CUD<\/jats:styled-content> alone and better premorbid social and occupational functioning remained significant predictors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Addressing <jats:styled-content style=\"fixed-case\">SUDs<\/jats:styled-content> and social and occupational goals in people with <jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content> may offer opportunities to prevent <jats:styled-content style=\"fixed-case\">SUDs<\/jats:styled-content> becoming more severe or entrenched. Further longitudinal research on recovery from <jats:styled-content style=\"fixed-case\">SU<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content> is needed to disentangle directions of influence and identify key targets for intervention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12067","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T19:22:40Z","timestamp":1374693760000},"page":"358-365","source":"Crossref","is-referenced-by-count":8,"title":["Predictors of substance use reduction in an epidemiological first\u2010episode psychosis cohort"],"prefix":"10.1111","volume":"8","author":[{"given":"Shane","family":"Rebgetz","sequence":"first","affiliation":[{"name":"Institute of Health &amp; Biomedical Innovation and School of Psychology &amp; Counselling Queensland University of Technology  Brisbane"},{"name":"Queensland Health, Metro\u2010North Health Service District Redcliffe\u2010Caboolture Mental Health 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Brisbane"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Cotton","sequence":"additional","affiliation":[{"name":"Orygen Youth Health Research Centre, Centre for Youth Mental Health University of Melbourne  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benno G.","family":"Schimmelmann","sequence":"additional","affiliation":[{"name":"University Hospital of Child and Adolescent Psychiatry University of Bern  Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick D.","family":"McGorry","sequence":"additional","affiliation":[{"name":"Orygen Youth Health Research Centre, Centre for Youth Mental Health University of Melbourne  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Lambert","sequence":"additional","affiliation":[{"name":"Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and 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