{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T06:45:50Z","timestamp":1759041950157},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,6,23]],"date-time":"2014-06-23T00:00:00Z","timestamp":1403481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The present study examined if any patient characteristics at baseline predicted depressive symptoms at 10 years and whether patients prone to depressive symptoms in the first year of treatment had a different prognosis in the following years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A total of 299 first\u2010episode psychosis (<jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content>) patients with schizophrenia spectrum disorders were assessed for depressive symptoms with <jats:styled-content style=\"fixed-case\">PANSS<\/jats:styled-content> depression item (g6) at baseline, and 1, 2, 5 and 10 years of follow up. At 10 years, depressive symptoms were also assessed with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>algary <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epression Scale for <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chizophrenia (CDSS). A <jats:styled-content style=\"fixed-case\">PANSS<\/jats:styled-content> g6\u2009\u2265\u20094 and <jats:styled-content style=\"fixed-case\">CDSS<\/jats:styled-content> score\u2009\u2265\u20096 were used as a cut\u2010off score for depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 122 (41%) patients were scored as depressed at baseline, 75 (28%) at 1 year, 50 (20%) at 2 years, 33 (16%) at 5 years, and 35 (19%) at 10 years of follow up. Poor childhood social functioning and alcohol use at baseline predicted depression at 10 years of follow up. Thirty\u2010eight patients were depressed at both baseline and 1 year follow up. This group had poorer symptomatic and functional outcome in the follow\u2010up period compared to a group of patients with no depression in the first year of treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Depressive symptoms are frequent among <jats:styled-content style=\"fixed-case\">FEP<\/jats:styled-content> patients at baseline but decrease after treatment because their general symptoms have been initiated. Patients with poor social functioning in childhood and alcohol use at baseline are more prone to have depressive symptoms at 10 years of follow up. Patients struggling with depressive symptoms in the first year of treatment should be identified as having poorer long\u2010term prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12163","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T10:21:35Z","timestamp":1403605295000},"page":"227-233","source":"Crossref","is-referenced-by-count":35,"title":["Depressive symptoms in first\u2010episode psychosis: a 10\u2010year follow\u2010up study"],"prefix":"10.1111","volume":"10","author":[{"given":"Nasrettin","family":"S\u00f6nmez","sequence":"first","affiliation":[{"name":"Division of Mental Health and Addiction Oslo University Hospital  Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Ivar","family":"R\u00f8ssberg","sequence":"additional","affiliation":[{"name":"Division of Mental Health and Addiction Oslo University Hospital  Oslo 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