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However, antidepressant medications commonly used to treat symptoms of anxiety may accelerate the onset of mania in these already at\u2010risk youth. Therefore, studies evaluating innovative non\u2010pharmacologic treatments for anxiety in this population are urgently needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects participated in 12 weekly sessions of mindfulness\u2010based cognitive therapy for children (<jats:styled-content style=\"fixed-case\">MBCT\u2010C<\/jats:styled-content>), a manualized group psychotherapeutic intervention utilizing cognitive behavioural principles and mindfulness exercises to increase regulation of attention and non\u2010judgmental acceptance of present moment thoughts, emotions and experiences. Independent raters administered symptoms rating scales prior to each treatment session. <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>pearman correlations and paired\u2010samples signed rank tests were used to examine outcomes. After\u2010intervention surveys and session transcripts were reviewed to assess feasibility and acceptability of the intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants included 10 youth (mean<jats:sub>age<\/jats:sub>\u2009=\u200913.2; 80% girls; 40% biracial) with generalized, social and\/or separation anxiety disorders, and a parent with bipolar disorder. Clinician\u2010rated anxiety was significantly reduced after intervention (mean<jats:sub>before<\/jats:sub>\u2009=\u200911.1; mean<jats:sub>after<\/jats:sub>\u2009=\u20094.3; <jats:styled-content style=\"fixed-case\"><jats:italic>P<\/jats:italic><\/jats:styled-content>\u2009&lt;\u20090.01), as well as youth\u2010rated trait anxiety (<jats:styled-content style=\"fixed-case\"><jats:italic>P<\/jats:italic><\/jats:styled-content>\u2009=\u20090.03). Parent\u2010rated emotion regulation significantly increased from before to after intervention (<jats:styled-content style=\"fixed-case\"><jats:italic>P<\/jats:italic><\/jats:styled-content>\u2009=\u20090.05). Increases in mindfulness were associated with decreases in anxiety (<jats:styled-content style=\"fixed-case\"><jats:italic>P<\/jats:italic><\/jats:styled-content>\u2009=\u20090.03). Finally, children and parents\/guardians reported high levels of feasibility, acceptability and usefulness of the intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Findings support the feasibility, acceptability and preliminary efficacy of <jats:styled-content style=\"fixed-case\">MBCT\u2010C<\/jats:styled-content> for treating anxiety in youth at risk for bipolar disorder. Future controlled and larger studies are needed to confirm these preliminary findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12216","type":"journal-article","created":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T17:54:29Z","timestamp":1421171669000},"page":"426-434","source":"Crossref","is-referenced-by-count":80,"title":["Mindfulness\u2010based cognitive therapy for youth with anxiety disorders at risk for bipolar disorder: a pilot trial"],"prefix":"10.1111","volume":"10","author":[{"given":"Sian","family":"Cotton","sequence":"first","affiliation":[{"name":"Department of Family and Community Medicine University of Cincinnati College of Medicine  Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine  Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M.","family":"Luberto","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine University of 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