{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T16:01:28Z","timestamp":1762272088813},"reference-count":49,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,2,11]],"date-time":"2017-02-11T00:00:00Z","timestamp":1486771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009128","name":"Research for Patient Benefit Programme","doi-asserted-by":"publisher","award":["PB\u2010PG\u20100609\u201016166"],"award-info":[{"award-number":["PB\u2010PG\u20100609\u201016166"]}],"id":[{"id":"10.13039\/501100009128","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Studies of potential interventions for asymptomatic individuals at risk of severe mental disorders (ie, clinical stage 0) have focused on genetic counselling or the views of adults with established disease. No study has interviewed youth at risk of bipolar disorders (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Qualitative analysis of interviews with asymptomatic adolescent offspring of adults with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OSBD<\/jats:styled-content>\u2009=\u20097) and unrelated parents with bipolar disorders (<jats:styled-content style=\"fixed-case\">PBD<\/jats:styled-content>\u2009=\u20096) to examine manifest and latent themes in the dialogue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Core themes in both groups were ignorance regarding the magnitude of risk of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> onset in offspring and greater concerns for the health of other family members than for oneself. Parents expressed anxieties in coping with the uncertainty about whether their children would inherit <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> and their desire to reduce this risk was partly driven by guilt and their sense of responsibility; <jats:styled-content style=\"fixed-case\">PBD<\/jats:styled-content> favoured the introduction of specialized clinical <jats:styled-content style=\"fixed-case\">OSBD<\/jats:styled-content> services. In contrast, the priority for <jats:styled-content style=\"fixed-case\">OSBD<\/jats:styled-content> was advice on coping with a parent with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>; <jats:styled-content style=\"fixed-case\">OSBD<\/jats:styled-content> favoured access to generic non\u2010clinical peer group support, which they perceived as less stigmatizing than specialist services.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study highlights that youth at risk of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> should be allowed to express their ideas on what interventions they believe are likely to be most beneficial for them, as their views may differ from other advocates who are routinely consulted, such as <jats:styled-content style=\"fixed-case\">PBD<\/jats:styled-content>. A noteworthy finding was that <jats:styled-content style=\"fixed-case\">OSBD<\/jats:styled-content> thought that being included in the clinical dialogue about their parents\u2019 <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> would decrease rather than increase their stress levels.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12421","type":"journal-article","created":{"date-parts":[[2017,2,11]],"date-time":"2017-02-11T07:02:42Z","timestamp":1486796562000},"page":"1112-1119","source":"Crossref","is-referenced-by-count":15,"title":["Should we intervene at stage 0? 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