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Associations between clinical and demographic measures at presentation and clinical diagnosis made at 1\u2009year were assessed with analysis of variance (ANOVA) and Chi\u2010square tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sample comprised 76% of patients with schizophrenia\u2010spectrum diagnoses, 9% with manic psychoses (MP) and 6% with depressive psychoses. Compared to the other 2 groups, patients who were diagnosed as having MP were younger, with higher education and shorter duration of untreated psychosis, and had higher Young Mania Rating Scale scores at presentation and lower Positive and Negative Syndrome Scale (PANSS) negative scores. Patients diagnosed at 1\u2009year as having depressive psychosis were older and more likely to be white, with the lowest PANSS positive scores at baseline. Patients diagnosed at 1\u2009year as having schizophrenia spectrum diagnoses were more likely to be males. Patients in the 3 diagnostic subgroups of psychosis differed on both clinical and demographic characteristics at presentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There were significant clinical and demographic differences at presentation between FEP patients who received different clinical diagnoses at 1\u2009year. Future work should determine the extent to which these differences can be used to guide clinical care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12511","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T04:52:48Z","timestamp":1508129568000},"page":"509-516","source":"Crossref","is-referenced-by-count":9,"title":["Clinical and demographic differences between patients with manic, depressive and schizophrenia\u2010spectrum psychoses presenting to Early Intervention Services in London"],"prefix":"10.1111","volume":"13","author":[{"given":"Adisha","family":"Kapila","sequence":"first","affiliation":[{"name":"Faculty of Life Sciences &amp; Medicine King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4174-2126","authenticated-orcid":false,"given":"Helen L.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Centre for Neuroimaging Sciences Institute of Psychiatry, Psychology &amp; Neuroscience, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Johnson","sequence":"additional","affiliation":[{"name":"Division of Psychiatry University College London London UK"},{"name":"Camden and Islington NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barnaby","family":"Major","sequence":"additional","affiliation":[{"name":"EQUIP, Hackney, East London NHS Foundation Trust London UK"},{"name":"Herefordshire Early Intervention Service, <sup>2<\/sup>gether NHS Foundation Trust Herefordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikola","family":"Rahaman","sequence":"additional","affiliation":[{"name":"Kensington, Chelsea, Westminster and Brent Early Intervention Service, Central &amp; North West London NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Joyce","sequence":"additional","affiliation":[{"name":"Lewisham Early Intervention Service, South London and Maudsley NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Chamberlain\u2010Kent","sequence":"additional","affiliation":[{"name":"Wandsworth Early Intervention Service, South West London &amp; St Georges\u2019 Mental Health NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Lawrence","sequence":"additional","affiliation":[{"name":"STEP, Southwark, South London and Maudsley NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan H.","family":"Young","sequence":"additional","affiliation":[{"name":"Centre for Neuroimaging Sciences Institute of Psychiatry, Psychology &amp; Neuroscience, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3051-0135","authenticated-orcid":false,"given":"James M.","family":"Stone","sequence":"additional","affiliation":[{"name":"Centre for Neuroimaging Sciences Institute of Psychiatry, Psychology &amp; Neuroscience, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,15]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"DSM 5","author":"American Psychiatric Association","year":"2013"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-015-0667-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(01)00559-4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1176\/ajp.154.11.1544","article-title":"Premorbid social functioning in schizophrenia and bipolar disorder: Similarities and differences","volume":"154","author":"Cannon M.","year":"1997","journal-title":"American Journal of Psychiatry"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.4.539"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199405000-00002"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2007.07.009"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12026"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7893.2007.00026.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12194"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60855-7"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.156.6.788"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-126"},{"key":"e_1_2_8_15_1","first-page":"113","article-title":"Clinician rating scales: Alcohol use scale (AUS), drug use scale (DUS), and substance abuse treatment scale (SATS). 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