{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:43:59Z","timestamp":1780325039494,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009362","name":"South London and Maudsley NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009362","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to compare clinical characteristics and treatment outcomes between children with Childhood\u2010onset schizophrenia spectrum disorders (COSS) and children with other severe non\u2010psychotic psychiatric conditions (non\u2010COSS), all admitted to a national mental health inpatient children's unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective study of all children discharged from a national children's inpatient unit in the United Kingdom, between 2009 and 2018. We compared functional and treatment outcomes and satisfaction with treatment in COSS with non\u2010COSS in the whole sample and separately for male and female patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 211 children (55% boys) were included in the sample. The mean age on admission was 129.7 months (10.8\u2009years; age range, 6\u201012).Twenty cases were diagnosed with COSS (9.5%). In the whole sample, COSS patients had significantly lower Children's Global Assessment Scale (CGAS) scores on admission compared to non\u2010COSS (<jats:italic>P<\/jats:italic> = .006). There was a trend towards children with COSS as a group having a longer admission (<jats:italic>M<\/jats:italic> = 194.6\u2009days, SD = 125.4) compared to non\u2010COSS (<jats:italic>M<\/jats:italic> = 135.8\u2009days, SD = 86.2), (<jats:italic>P<\/jats:italic> = .053). Females with COSS seemed to have more significant differences compared to females with non\u2010COSS, in particular, longer admissions (<jats:italic>P<\/jats:italic> = .016) and worse CGAS scores at discharge (<jats:italic>P<\/jats:italic> = .04), whilst in males, these differences seemed to be attenuated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Children with COSS have lower functioning at the point of inpatient admission and possibly longer admissions, but similar satisfaction with treatment at discharge from hospital compared with non\u2010COSS. Females with COSS may have worse functional outcomes compared to non\u2010COSS at discharge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12973","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T09:59:43Z","timestamp":1589968783000},"page":"412-419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Functional outcomes and patient satisfaction following inpatient treatment for childhood\u2010onset schizophrenia spectrum disorders vs non\u2010psychotic disorders in children in the United Kingdom"],"prefix":"10.1111","volume":"15","author":[{"given":"Hayley","family":"Galitzer","sequence":"first","affiliation":[{"name":"National and Specialist Acorn Lodge Inpatient Children's Unit, Child and Adolescent Mental Health Clinical Academic Group South London and the Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nefeli","family":"Anagnostopoulou","sequence":"additional","affiliation":[{"name":"National and Specialist Acorn Lodge Inpatient Children's Unit, Child and Adolescent Mental Health Clinical Academic Group South London and the Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Alba","sequence":"additional","affiliation":[{"name":"National and Specialist Acorn Lodge Inpatient Children's Unit, Child and Adolescent Mental Health Clinical Academic Group South London and the Maudsley NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6650-6018","authenticated-orcid":false,"given":"Jorge","family":"Gaete","sequence":"additional","affiliation":[{"name":"National and Specialist Acorn Lodge Inpatient Children's Unit, Child and Adolescent Mental Health Clinical Academic Group South London and the Maudsley NHS Foundation Trust  London UK"},{"name":"Faculty of Education Universidad de los Andes  Santiago Chile"},{"name":"Millennium Nucleus to Improve the Mental Health of Adolescents and Youths  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2598-0952","authenticated-orcid":false,"given":"Danai","family":"Dima","sequence":"additional","affiliation":[{"name":"Department of Psychology, School of Arts and Social Sciences City, University of London  London UK"},{"name":"Department of Neuroimaging Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4594-2646","authenticated-orcid":false,"given":"Marinos","family":"Kyriakopoulos","sequence":"additional","affiliation":[{"name":"National and Specialist Acorn Lodge Inpatient Children's Unit, Child and Adolescent Mental Health Clinical Academic Group South London and the Maudsley NHS Foundation Trust  London UK"},{"name":"Department of Child and Adolescent Psychiatry Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1976.01770060086012"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/chi.0b013e31807083fd"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-011-0212-4"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2007.01802.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/2045125318765725"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540260701486258"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1359104513493430"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2017.12.009"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2006.07.007"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-006-0553-z"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1983.01790100074010"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.158493"},{"key":"e_1_2_8_15_1","volume-title":"The ICD\u201010 classification of mental and behavioural disorders. 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