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However, research on the significance of anxiety in predicting remission and long\u2010term functioning in first\u2010episode psychosis (FEP) is still scarce. This study investigated the effects of anxiety and obsessive\u2010compulsive symptoms (OCS) on clinical and functional improvement in individuals with FEP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>FEP patients (N = 97) aged 18\u201040\u2009years were recruited from the University Hospital District of Helsinki and the City of Helsinki. Psychotic and anxiety symptoms were measured using the Brief Psychiatric Rating Scale. Obsessive\u2010compulsive symptoms were assessed using the Obsessive\u2010Compulsive Inventory (OCI\u2010R), and functioning was evaluated using the Social and Occupational Functioning Assessment Scale (SOFAS). Follow\u2010up measurements were performed at 2 and 12\u2009months. We specifically studied whether anxiety and obsessive\u2010compulsive symptoms at the 2\u2010month follow\u2010up assessment, at a time when the initial treatment response had been achieved, would predict outcomes at 12\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Symptoms of anxiety and OCS correlated moderately with each other and psychotic symptoms, but at the 12\u2010month follow\u2010up, OCS no longer correlated significantly with psychotic and anxiety symptoms. When the level of psychotic symptoms was adjusted for, more severe OCS at the 2\u2010month follow\u2010up was associated with a lower rate of remission at 12\u2009months, whereas a higher level of anxiety symptoms at 2 months was associated with better functioning at 12\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>OCS may be predictive of poorer clinical outcomes, whereas anxiety symptoms may predict better functional outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.12986","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T14:18:18Z","timestamp":1591625898000},"page":"569-576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Anxiety symptoms in first\u2010episode psychosis"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3647-2889","authenticated-orcid":false,"given":"Boris","family":"Karpov","sequence":"first","affiliation":[{"name":"Department of Psychiatry University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuula","family":"Kiesepp\u00e4","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maija","family":"Lindgren","sequence":"additional","affiliation":[{"name":"Department of Public Health Solutions, Mental Health Unit Finnish Institute for Health and Welfare  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asko","family":"Wegelius","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Helsinki and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaana","family":"Suvisaari","sequence":"additional","affiliation":[{"name":"Department of Public Health Solutions, Mental Health Unit Finnish Institute for Health and Welfare  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp148"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12250"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1192\/S0007125000291496"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.3.441"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2004.09.003"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.07.030"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.07.039"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000001030"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbu169"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.07r03618"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-12952-5","volume-title":"Obsessive\u2010compulsive symptoms in schizophrenia","author":"Haan L.","year":"2015"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.10.011"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2006.09.013"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2009.05.008"},{"key":"e_1_2_7_16_1","volume-title":"Structured Clinical Interview for DSM\u2010IV\u2010TR Axis I disorders, Research version, Patient edition. 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