{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:05:20Z","timestamp":1783469120451,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["Research Seed Funding (Pilot Study) at IMH\/WH"],"award-info":[{"award-number":["Research Seed Funding (Pilot Study) at IMH\/WH"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>There is a growing appreciation that subthreshold but clinically elevated levels of autistic traits are clinically relevant. This study examined autistic traits in Singaporean patients with first\u2010episode psychosis and their association with 1\u2010year psychosis recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The relationship between baseline patient characteristics, autistic traits (measured with autism screening questionnaires) and psychosis recovery outcomes at 1\u2010year were examined in 180 adults in the Early Intervention Psychosis Programme in Singapore.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 180 participants, 50 (27.8%) had clinically elevated above screening\u2010cut off levels of autistic traits on the self\u2010reported 10\u2010item Autism Spectrum Quotient and 8 (4.4%) on the staff\u2010rated Autism Spectrum Disorder in Adults Screening Questionnaire. At baseline, those with more autistic traits were more likely to be unemployed, economically inactive (ie, students or homemakers); and to have diagnoses of mood disorder with psychotic features, brief psychotic disorder or psychotic disorder not otherwise specified as compared to schizophrenia spectrum and delusional disorder diagnoses. Although most participants showed improvements in their clinical outcomes at 1\u2010year, those with higher autistic traits improved less in the Positive and Negative Syndrome Scale general psychopathology scale and in Global Assessment of Functioning symptomatology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Autistic traits are common in those with first\u2010episode psychosis and may be associated with poorer clinical outcomes. Validated screening tools should be developed in this population to support earlier reporting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.13021","type":"journal-article","created":{"date-parts":[[2020,7,25]],"date-time":"2020-07-25T06:15:33Z","timestamp":1595657733000},"page":"849-855","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Autistic traits in first\u2010episode psychosis: Rates and association with 1\u2010year recovery outcomes"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0224-3375","authenticated-orcid":false,"given":"Shushan","family":"Zheng","sequence":"first","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3906-4736","authenticated-orcid":false,"given":"Yi Chian","family":"Chua","sequence":"additional","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6248-2565","authenticated-orcid":false,"given":"Charmaine","family":"Tang","sequence":"additional","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles Ming\u2010Yee","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychiatry Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edimansyah","family":"Abdin","sequence":"additional","affiliation":[{"name":"Research Division Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki Wei Qi","family":"Lim","sequence":"additional","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"},{"name":"Department of Psychology National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astelle Shiyun","family":"Koh","sequence":"additional","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapna","family":"Verma","sequence":"additional","affiliation":[{"name":"Early Psychosis Intervention Programme Institute of Mental Health  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iliana","family":"Magiati","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychiatry Institute of Mental Health  Singapore"},{"name":"Department of Psychology National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2011.11.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.3.441"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291718000600"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2008.10.004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2019.112623"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chc.2013.04.005"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.5.524"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12039"},{"key":"e_1_2_8_10_1","volume-title":"Structured clinical interview for DSM\u2010IV Axis I disorders (SCID\u2010I), clinician version","author":"First M. 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