{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:30:49Z","timestamp":1753878649040,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present study aimed to evaluate data from patients admitted to the first\u2010episode psychotic (FEP) outpatient clinic at the Hospital of Clinics of the Federal University of Pernambuco from July 2018 to July 2021, seeking to identify factors related to better clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was conducted using a convenience sample, including all patients between 15 and 65\u2009years of age who were admitted to the FEP outpatient clinic from July 2018 to July 2021. Descriptive statistical analysis was performed using mean and standard deviation or median and interquartile range for continuous quantitative variables, and absolute number\/percentage for qualitative variables. Paired <jats:italic>T<\/jats:italic>\u2010test, a parametric test, was used to compare PANSS scores upon admission and after 6\u2009months. Spearman's correlation test was employed to assess the correlation between duration of untreated psychosis (DUP) and treatment response with other variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sample consisted of 85.3% male individuals, with 50% of patients aged between 19 and 30\u2009years, and 82% residing in the metropolitan area of Recife. Seventy percent of patients responded to the treatment implemented by the outpatient clinic, and only 30% required psychiatric hospitalization within 6\u2009months of follow\u2010up. The majority of patients had a history of psychoactive substance use (82.4%); however, the use of these substances did not impact the prognosis within the analysed sample. The median DUP was 4\u2009weeks, and a shorter DUP was associated with a lower probability of psychiatric hospitalization and a greater treatment response (reduction &gt;50% in PANSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A shorter DUP was associated with a lower likelihood of psychiatric hospitalization and a greater treatment response. Furthermore, the specialized early psychosis outpatient clinic itself appears to yield positive outcomes, as 70% of the treated patients exhibited a positive treatment response.<\/jats:p><\/jats:sec>","DOI":"10.1111\/eip.13563","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T05:29:39Z","timestamp":1716442179000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with improved outcomes in the first psychotic episode at a specialized outpatient clinic in northeastern Brazil"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0407-2637","authenticated-orcid":false,"given":"Isabela","family":"de Fatima Pina de Almeida","sequence":"first","affiliation":[{"name":"Department of Neuropsychiatry Medical Sciences Center, Federal University of Pernambuco  Recife PE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo Ferreira Castello Branco","family":"Vilar","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Medical Sciences Center, Federal University of Pernambuco  Recife PE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamim Figueiredo Braga Pires","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Medical Science Center Federal University of Pernambuco  Recife PE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Coelho","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Medical Sciences Center, Federal University of Pernambuco  Recife PE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Medical Sciences Center, Federal University of Pernambuco  Recife PE Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2021.03.013"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-199801001-00006"},{"issue":"6","key":"e_1_2_10_5_1","first-page":"677","article-title":"Impact of duration of untreated psychosis in short\u2010term response to treatment and outcome in antipsychotic na\u00efve first\u2010episode psychosis. Early intervention","volume":"14","author":"Cavalcante D. A.","year":"2020","journal-title":"Psychiatry"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.13252"},{"issue":"6","key":"e_1_2_10_7_1","first-page":"555","article-title":"Comparison of early intervention services vs treatment as usual for early\u2010phase psychosis. JAMA","volume":"75","author":"Correll C. U.","year":"2018","journal-title":"Psychiatry"},{"key":"e_1_2_10_8_1","unstructured":"deOliveira J. I. M.Primeiro epis\u00f3dio psic\u00f3tico: fatores de risco fatores preditivos e diagn\u00f3stico diferencial 46 2019 Disserta\u00e7\u00e3o (Mestrado Integrado em Medicina). 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