{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:48Z","timestamp":1787014128042,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Early Intervention Psych"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this study was to compare the multidisciplinary vocational intervention, Morpheus, with standard vocational rehabilitation for young adults with incident schizophrenia undergoing the OPUS specialised early intervention programme. The study evaluated whether the type of vocational intervention was related to attachment to the labour market and educational system, outpatient contacts, hospital admissions and psychotropic drug use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study included patients of the OPUS programme in the period from January 1, 2014, to December 31, 2019. Patients at Aarhus University Hospital Psychiatry (Aarhus) were offered the Morpheus intervention, while patients at Aalborg University Hospital (Aalborg) received standard vocational rehabilitation. The study used register and clinical data. The analyses involved logistic and linear regression presented as crude and adjusted models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 404 OPUS patients from Aarhus and 246 OPUS patients from Aalborg, patients participating in the Morpheus intervention (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009116) were more likely to be employed or enrolled in education 2 and 4\u2009years after diagnosis compared with patients undergoing standard vocational intervention (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009130). Specifically, the adjusted odds ratio for employment was 1.14 (0.37; 3.45) and 1.51 (0.70; 3.27) at 2 and 4\u2009years, respectively. Morpheus patients were less likely to attend somatic outpatient contacts, which involve consultations or treatment for physical health conditions, as well as psychiatric outpatient contacts. Furthermore, they were less likely to be admitted to somatic departments or to redeem antipsychotic medication. However, Morpheus patients had a higher likelihood of being admitted to psychiatric departments during the periods 0\u20132 and 2\u20134\u2009years after diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Young adults with incident schizophrenia receiving the Morpheus intervention within the OPUS treatment did not show statistically significant increased odds of employment or education enrolment compared to those in standard vocational rehabilitation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/eip.70062","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T06:34:43Z","timestamp":1750228483000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Vocational Rehabilitation in Young Adults With Incident Schizophrenia\u2014A Danish Retrospective Cohort Study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2011-7877","authenticated-orcid":false,"given":"Pernille","family":"Pedersen","sequence":"first","affiliation":[{"name":"Department of Public Health Aarhus University  Aarhus Denmark"},{"name":"DEFACTUM Central Denmark Region  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birthe Bruun","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Psychosis Aarhus University Hospital Psychiatry  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5096-2281","authenticated-orcid":false,"given":"Ditte Lammers","family":"Vernal","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0110-0895","authenticated-orcid":false,"given":"Matilde Poulsen","family":"Rydborg","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6194-1099","authenticated-orcid":false,"given":"Christiane","family":"Gasse","sequence":"additional","affiliation":[{"name":"Department of Affective Disorders Aarhus University Hospital Psychiatry  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"},{"name":"Psychosis Research Unit Aarhus University Hospital Psychiatry  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5660-0393","authenticated-orcid":false,"given":"Ole","family":"Mors","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"},{"name":"Psychosis Research Unit Aarhus University Hospital Psychiatry  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2021.03.013"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-022-01228-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796014000419"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/08039488.2014.973902"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"345","article-title":"Employment Outcomes for People With Schizophrenia Spectrum Disorder: A Meta\u2010Analysis of Randomized Controlled Trials","volume":"30","author":"Carmona V. 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