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The efficacy of donor leukocyte infusions (<jats:styled-content style=\"fixed-case\">DLI<\/jats:styled-content>) is excellent in chronic phase chronic myeloid leukaemia but limited in other disorders. We present a patient who relapsed 10 months after reduced intensity conditioning allo\u2010<jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> for a myelodysplastic\/ myeloproliferative neoplasm with myelofibrosis despite receiving escalating doses of <jats:styled-content style=\"fixed-case\">DLI<\/jats:styled-content> for incomplete chimerism. He finally achieved complete remission with full whole blood and T\u2010cell donor chimerism after <jats:styled-content style=\"fixed-case\">DLI<\/jats:styled-content> preceded by lymphodepletion chemotherapy. This case demonstrates that chemotherapy prior to <jats:styled-content style=\"fixed-case\">DLI<\/jats:styled-content> is a useful approach for treating relapses of relatively slowly progressive diseases, such as myeloproliferative diseases or myelodysplastic syndromes.<\/jats:p>","DOI":"10.1111\/ejh.12034","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T08:42:08Z","timestamp":1351586528000},"page":"76-78","source":"Crossref","is-referenced-by-count":0,"title":["Lymphodepletion chemotherapy followed by donor leukocytes for post\u2010transplantation relapse of myelofibrosis after previous donor leukocyte infusion failure"],"prefix":"10.1111","volume":"90","author":[{"given":"Emma Lucy","family":"Neave","sequence":"first","affiliation":[{"name":"Department of Haematology Imperial College at Hammersmith Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heike","family":"Schwarb","sequence":"additional","affiliation":[{"name":"Innere Medizin and Onkologie Kantonsspital Baden Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdurrazag","family":"Shlebak","sequence":"additional","affiliation":[{"name":"Department of Haematology Imperial College at Hammersmith Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Mark","family":"Layton","sequence":"additional","affiliation":[{"name":"Department of Haematology Imperial College at Hammersmith Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane F.","family":"Apperley","sequence":"additional","affiliation":[{"name":"Department of Haematology Imperial College at Hammersmith Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiri","family":"Pavlu","sequence":"additional","affiliation":[{"name":"Department of Haematology Imperial College at Hammersmith Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,29]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403967"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.10.023"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.8.2712"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1997.15.2.433"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-05-2004"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050732"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.5.2591"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2004.12.003"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1310"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-05-090340"}],"container-title":["European Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fejh.12034","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejh.12034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:49:23Z","timestamp":1700614163000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejh.12034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,29]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/ejh.12034"],"URL":"https:\/\/doi.org\/10.1111\/ejh.12034","archive":["Portico"],"relation":{},"ISSN":["0902-4441","1600-0609"],"issn-type":[{"value":"0902-4441","type":"print"},{"value":"1600-0609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,29]]}}}