{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T15:33:02Z","timestamp":1700839982359},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,1,25]],"date-time":"2014-01-25T00:00:00Z","timestamp":1390608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Isolated myeloid sarcoma is a rare presentation of acute myeloid leukemia. There are limited data available concerning the prognostic relevance and the right treatment strategy for this clinical scenario. Here, we report a case of acute myeloid leukemia with extensive lesions and fractures in multiple bones in a 64\u2010yr\u2010old male patient. Remarkably, treatment with a high\u2010dose cytarabine regimen led to rapid remineralization of all bone lesions and recovery of the patient's mobility within a few weeks. Thereby, surgical treatment and radiotherapy could be avoided, supporting the role of intensive induction and standard consolidation chemotherapy as first\u2010line treatment for myeloid sarcoma.<\/jats:p>","DOI":"10.1111\/ejh.12254","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T12:25:00Z","timestamp":1387455900000},"page":"537-540","source":"Crossref","is-referenced-by-count":3,"title":["Rapid remineralization of multiple disseminated bone lesions after high\u2010dose cytarabine in a patient with isolated myeloid sarcoma"],"prefix":"10.1111","volume":"92","author":[{"given":"Sebastian","family":"Br\u00e4hler","sequence":"first","affiliation":[{"name":"Department II of Internal Medicine University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indra","family":"Thielen","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine and Center for Integrated Oncology K\u00f6ln\u2010Bonn University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Schwabe","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Engels","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl\u2010Anton","family":"Kreuzer","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine and Center for Integrated Oncology K\u00f6ln\u2010Bonn University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine and Center for Integrated Oncology K\u00f6ln\u2010Bonn University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sascha","family":"Ans\u00e9n","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine and Center for Integrated Oncology K\u00f6ln\u2010Bonn University of Cologne Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,25]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-347229"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.7.1800"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1986.4.6.912"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.4.690"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404491"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1997.15.2.466"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.041418"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-07-235358"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.02.057"}],"container-title":["European Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fejh.12254","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejh.12254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T12:38:13Z","timestamp":1696336693000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejh.12254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,25]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/ejh.12254"],"URL":"https:\/\/doi.org\/10.1111\/ejh.12254","archive":["Portico"],"relation":{},"ISSN":["0902-4441","1600-0609"],"issn-type":[{"value":"0902-4441","type":"print"},{"value":"1600-0609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,25]]}}}