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This review presents currently available platelet\u2010related markers available on automated haematology analysers and commonly used methods for testing platelet function. The test principles, advantages and disadvantages of each test are described. We also evaluate the current literature regarding the clinical utility of the test for prediction of bleeding in thrombocytopenia in haematological and oncological diseases. We find that several platelet\u2010related markers are available, but information about the clinical utility in thrombocytopenia is limited. Studies support that mean platelet volume (<jats:styled-content style=\"fixed-case\">MPV<\/jats:styled-content>) can aid diagnosing the cause of thrombocytopenia and low <jats:styled-content style=\"fixed-case\">MPV<\/jats:styled-content> may be associated with bleeding in thrombocytopenia. Flow cytometry, platelet aggregometry and platelet secretion tests are used to diagnose specific platelet function defects. The flow cytometric activation marker <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2010selectin and surface coverage by the Cone\u2010and\u2010Plate[let] analyser predict bleeding in selected thrombocytopenic populations. To fully uncover the clinical utility of platelet\u2010related tests, information about the prevalence of platelet function defects in thrombocytopenic conditions is required. Finally, knowledge of the performance in thrombocytopenic samples from patients is essential.<\/jats:p>","DOI":"10.1111\/ejh.12262","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T08:41:52Z","timestamp":1389256912000},"page":"367-376","source":"Crossref","is-referenced-by-count":77,"title":["An overview of platelet indices and methods for evaluating platelet function in thrombocytopenic patients"],"prefix":"10.1111","volume":"92","author":[{"given":"Pernille J.","family":"Vinholt","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry and Pharmacology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Mette","family":"Hvas","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry Aarhus University Hospital Aarhus 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