{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:22:21Z","timestamp":1761740541480},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The epidemiology of myelodysplastic syndromes (<jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content>) differs among countries. Here, we present the first epidemiological indices determined for Poland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010one haematological centres participated in the study. Patients diagnosed with <jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content> and acute myeloid leukaemia (<jats:styled-content style=\"fixed-case\">AML<\/jats:styled-content>) with 20\u201329% blasts were enrolled. Data collection was conducted for strictly predefined period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall crude incidence rate for all <jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content> subtypes was 1.95 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.81\u20132.09) per 100 000 person\u2010years: 2.46 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 2.24\u20132.69) for males and 1.47 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.31\u20131.65) for females; after excluding <jats:styled-content style=\"fixed-case\">AML<\/jats:styled-content> cases, the indices were as follows: 2.35 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 2.08\u20132.66) for males and 1.27 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.08\u20131.5) for females. Prevalence rate was 6.2 per 100 000 persons (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 5.96\u20136.45), that is 6.86 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 6.49\u20137.24) for males and 5.58 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 5.26\u20135.92) for females. Both incidence and prevalence increased with increasing age. The most frequently diagnosed <jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content> subtype was refractory cytopenia with multilineage dysplasia (<jats:styled-content style=\"fixed-case\">RCMD<\/jats:styled-content>), responsible for 30.3% of all newly diagnosed <jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content>s.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RCMD<\/jats:styled-content> is the most frequent <jats:styled-content style=\"fixed-case\">MDS<\/jats:styled-content> subtype in Poland. Incidence and prevalence indices are lower than those reported for other populations, which probably results from inadequate diagnosis of potential cases of this disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.12814","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T17:09:48Z","timestamp":1476205788000},"page":"154-159","source":"Crossref","is-referenced-by-count":2,"title":["Are myelodysplastic syndromes underdiagnosed in Poland? 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