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In addition, incidence of opportunistic infections and of <jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content>\u2010defining malignancies declined. Nevertheless, aggressive non\u2010Hodgkin\u2019s lymphoma still remains the leading cause of <jats:styled-content style=\"fixed-case\">AIDS<\/jats:styled-content>\u2010related deaths. The availability of <jats:styled-content style=\"fixed-case\">cART<\/jats:styled-content>, however, significantly improved the therapeutic options for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients with lymphomas. Diffuse large B\u2010cell lymphoma, Burkitt\u2019s lymphoma, or Hodgkin lymphoma has increasingly become curable diseases. In light of these favorable developments in the treatment of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010associated lymphomas, reduction in treatment\u2010associated toxicities and further improvement of outcome of patients with advanced immune suppression are major requirements for future clinical trials. This review summarizes the current treatment landscape and gives an overview on future needs in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients with lymphoma.<\/jats:p>","DOI":"10.1111\/ejh.13082","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T06:20:53Z","timestamp":1523946053000},"page":"119-126","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Malignant lymphoma in the <scp>HIV<\/scp>\u2010positive patient"],"prefix":"10.1111","volume":"101","author":[{"given":"Anne","family":"Meister","sequence":"first","affiliation":[{"name":"Department of Medicine I University Hospital of Cologne  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Hentrich","sequence":"additional","affiliation":[{"name":"Department of Medicine III Red Cross Hospital Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Wyen","sequence":"additional","affiliation":[{"name":"Department of Medicine I University Hospital of Cologne  Cologne Germany"},{"name":"Praxis am Ebertplatz  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7958-4664","authenticated-orcid":false,"given":"Kai","family":"H\u00fcbel","sequence":"additional","affiliation":[{"name":"Department of Medicine I University Hospital of Cologne  Cologne Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,22]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25547"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31817efb54"},{"key":"e_1_2_15_4_1","first-page":"1","article-title":"Revised surveillance case definitions for HIV infection among adults, adolescents, and children aged <18\u00a0months and for HIV infection and AIDS among children aged 18\u00a0months to <13\u00a0years\u2013United States, 2008","volume":"57","author":"Schneider E","year":"2008","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-08-301531"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.8.2339"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-26857-6"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000222"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25530"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji072"},{"key":"e_1_2_15_11_1","first-page":"340","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Raphael MSJ","year":"2008"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2013.1.382"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.8800"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)01020-8"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506816"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki050"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-015-2447-3"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2013.094318"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.11.3909"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13221"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/35000501"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-04-498964"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.5450"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(06)70664-7"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1437"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.4684"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32834f30fa"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-231613"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-253039"},{"key":"e_1_2_15_30_1","unstructured":"WilsonWH Sin\u2010HoJ PitcherBN BN et\u00a0al.Phase III randomized study of R\u2010CHOP versus DA\u2010EPOCH\u2010R and molecular analysis of untreated diffuse large B\u2010cell lymphoma. 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