{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T06:04:31Z","timestamp":1775714671843,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T00:00:00Z","timestamp":1583193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Primary renal lymphoma (PRL) is defined as a non\u2010Hodgkin lymphoma (NHL) restricted to kidneys without extensive nodal disease. The literature on epidemiology and outcome in PRL is limited to case reports and small case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We utilized Surveillance, Epidemiology, and End Result database (1984\u20102015) to study the demographic, clinical, and pathological characteristics of PRL. We conducted analysis to assess factors associated with overall survival (OS) and cause\u2010specific survival (CSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 599 (0.17% of all NHL) patients were eligible for the study. The age\u2010adjusted incidence was 0.035\/100,000 population and is increasing. The median age was 72\u00a0years, and most of the patients were Caucasians and were males. Most of the patients had unilateral tumors, and diffuse large B\u2010cell lymphoma (DLBCL) was the most common histologic type. The median OS was 112\u00a0months, while median CSS was not reached. Age\u00a0\u2265\u00a060\u00a0years was the strongest independent risk factor for worse OS and CSS, while non\u2010DLBCL histology was associated with better OS and CSS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Primary renal lymphoma is a rare lymphoma with increasing incidence in more recent years. In this study, we describe demographic, clinical, and pathological characteristics of PRL and factors affecting survival among these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.13360","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T11:44:11Z","timestamp":1574768651000},"page":"390-399","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Primary renal lymphoma: A population\u2010based analysis using the SEER program (1973\u20102015)"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7231-2623","authenticated-orcid":false,"given":"Alankrita","family":"Taneja","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Wayne State University School of Medicine Detroit MI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Medical Oncology Brigham and Women\u2019s Hospital Boston MA USA"},{"name":"Dana\u2010Farber Cancer Institute Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhinav B.","family":"Chandra","sequence":"additional","affiliation":[{"name":"Yuma Regional Cancer Center Yuma AZ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,3]]},"reference":[{"issue":"3","key":"e_1_2_5_2_1","first-page":"163","article-title":"Acute renal failure due to bilateral lymphomatous infiltrates. 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