{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:58:15Z","timestamp":1789091895265,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to analyze the outcomes of children with Diamond\u2010Blackfan anemia (DBA) treated in Brazil with hematopoietic cell transplantation (HCT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective analysis of 44 pediatrics patients transplanted between 1990 and 2018. The median age of patients was 5\u00a0years, and 57% were male. Twenty\u2010five received their first HCT from an HLA\u2010matched sibling donor (MSD), 12 from a HLA matched unrelated bone marrow donor (MUD 10\/10, n\u00a0=\u00a012) and 7 other HLA mismatched donors (MMD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After a median follow\u2010up of 4\u00a0years, estimate 5\u2010year overall survival (OS) for the entire cohort was 70%, 80% for MSD group, 73% for MUD, and 29% for MMD. Thirty\u2010eight out of the 44 evaluable patients engrafted successfully. Primary and secondary graft failure was observed in five and three patients, respectively. Rates of grade II\u2010IV and III\u2010IV acute graft\u2010versus\u2010host disease (aGVHD) were 25% and 18%, respectively. Nine patients developed chronic GVHD (cGVHD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Overall survival rates observed after HLA matched donors transplant for DBA were comparable to those reported from higher\u2010income countries and international registries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.13463","type":"journal-article","created":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T09:10:51Z","timestamp":1591866651000},"page":"426-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Hematopoietic cell transplantation for Diamond Blackfan anemia: A report from the Pediatric Group of the Brazilian Bone Marrow Transplantation Society"],"prefix":"10.1111","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6007-8908","authenticated-orcid":false,"suffix":"Junior","given":"Luiz Guilherme","family":"Darrigo","sequence":"first","affiliation":[{"name":"Hospital 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