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PML has been reported only rarely in multiple myeloma patients, and its presenting features and natural history in this population are not well known. We describe six cases of PML among multiple myeloma patients treated at our institution between 2013 and 2022, including two that developed on or shortly after treatment with recently developed BCMA\u2010directed immunotherapies.<\/jats:p>","DOI":"10.1111\/ejh.13909","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T03:18:26Z","timestamp":1670210306000},"page":"322-329","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Progressive multifocal leukoencephalopathy in multiple myeloma"],"prefix":"10.1111","volume":"110","author":[{"given":"Brian W.","family":"Hoeynck","sequence":"first","affiliation":[{"name":"Department of Medicine, Perelman School of Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam D.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Abramson Cancer Center, 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