{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:18:10Z","timestamp":1762957090706},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1111\/ejh.13943","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T11:35:41Z","timestamp":1676374541000},"page":"774-777","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The net clinical benefit of targeted agents in the upfront treatment of elderly\/unfit chronic lymphocytic leukemia patients: Results of network meta\u2010analysis"],"prefix":"10.1111","volume":"110","author":[{"given":"Stefano","family":"Molica","sequence":"first","affiliation":[{"name":"Department Haematology Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Allsup","sequence":"additional","affiliation":[{"name":"Department Haematology Hull University Teaching Hospitals NHS Trust  Hull UK"},{"name":"Centre for Biomedicine Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Polliack","sequence":"additional","affiliation":[{"name":"Hadassah University Hospital and Hebrew University Medical School  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Giannarelli","sequence":"additional","affiliation":[{"name":"Biostatistics Unit, Scientific Directorate Fondazione Policlinico Universitario A. Gemelli, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"e_1_2_1_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26367"},{"key":"e_1_2_1_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2020.09.019"},{"key":"e_1_2_1_5_4_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0031"},{"key":"e_1_2_1_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2021.06.010"},{"key":"e_1_2_1_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2020.08.017"},{"key":"e_1_2_1_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2020.1811271"},{"key":"e_1_2_1_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2020.10.012"},{"key":"e_1_2_1_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0564-1"},{"key":"e_1_2_1_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1741"},{"key":"e_1_2_1_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-019-0602-x"},{"key":"e_1_2_1_5_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1812836"},{"key":"e_1_2_1_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1817073"},{"key":"e_1_2_1_5_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2021-152319"},{"key":"e_1_2_1_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(22)00293-5"},{"key":"e_1_2_1_5_16_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.279012"},{"key":"e_1_2_1_5_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-021-01485-x"},{"key":"e_1_2_1_5_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01181"},{"key":"e_1_2_1_5_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDoa2200006"},{"key":"e_1_2_1_5_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2022.2087072"},{"key":"e_1_2_1_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15690"},{"key":"e_1_2_1_5_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41669\u2010022\u201000375\u2010x"}],"container-title":["European Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejh.13943","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ejh.13943","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejh.13943","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T15:41:27Z","timestamp":1692632487000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejh.13943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,24]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/ejh.13943"],"URL":"https:\/\/doi.org\/10.1111\/ejh.13943","archive":["Portico"],"relation":{},"ISSN":["0902-4441","1600-0609"],"issn-type":[{"value":"0902-4441","type":"print"},{"value":"1600-0609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,24]]},"assertion":[{"value":"2022-12-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}