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In the case of long\u2010term remission (\u22655\u2009years; <jats:italic>n<\/jats:italic>\u2009=\u200927), peripheral blood was tested for minimal residual disease (MRD) by t(11;14)\u2010 and IGH\u2010PCR at the last follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten\u2010year overall survival (OS), progression\u2010free survival (PFS), and freedom from progression (FFP) after first\u2010line ASCT were 64%, 52%, and 59% versus after second\u2010line ASCT 50%, 20%, and 20%, respectively. Five\u2010year OS, PFS, and FFP for the first\u2010line cohort were 79%, 63%, and 69%, respectively. Five\u2010year OS, PFS, and FFP after second\u2010line ASCT were 60%, 30%, and 30%, respectively. Treatment\u2010related mortality (3\u2009months after ASCT) was 1.5%. So far 26 patients developed sustained long\u2010term clinical and molecular complete remissions of up to 19\u2009years following ASCT in first treatment line.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sustained long\u2010term clinical and molecular remissions are achievable following ASCT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.13985","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T23:59:11Z","timestamp":1682380751000},"page":"220-228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Long\u2010term outcome in patients with mantle cell lymphoma following high\u2010dose therapy and autologous stem cell transplantation"],"prefix":"10.1111","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1496-1377","authenticated-orcid":false,"given":"Bernd","family":"Metzner","sequence":"first","affiliation":[{"name":"Department of Oncology 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