{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:59:51Z","timestamp":1767650391568,"version":"3.40.5"},"reference-count":55,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Allogeneic stem cell transplantation (allo\u2010SCT) may have a curative potential due to the graft versus lymphoma effect. In this study, we aimed to compare transplant outcomes between refractory\u2010T\u2010NHL (ref\u2010NHL) and Chemosensitive\u2010T\u2010NHL (CS\u2010T\u2010NHL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We retrospectively reviewed the records of 26 ref\u2010NHL and 29 CS\u2010T\u2010NHL consecutive patients who underwent allo\u2010SCT at our center and compared the transplant outcomes between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients were heavily pretreated with 27% of patients relapsing post\u2010auto\u2010SCT and two patients in the ref\u2010T\u2010NHL post\u2010allo\u2010SCT. Patients were transplanted mainly from unrelated donors. There were no differences in leucocytes and platelet engraftment between the two groups. At 3\u2009years, the relapse incidence was 34% in Ref\u2010TNHL and 19% in CS\u2010TNHL (<jats:italic>p<\/jats:italic>\u2009=\u2009.33), with non\u2010relapse mortality rates of 28% and 22%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u2009.52). Female patients and those with a previous auto\u2010SCT had lower relapse incidence (<jats:italic>p<\/jats:italic>\u2009=\u2009.045, <jats:italic>p<\/jats:italic>\u2009=\u2009.003). The 3\u2010year overall survival was 39% in Ref\u2010TNHL and 56% in CS\u2010TNHL (<jats:italic>p<\/jats:italic>\u2009=\u2009.15). Trends for improved progression\u2010free survival (PFS) and graft\u2010versus\u2010host disease relapse\u2010free survival (GRFS) were observed in the CS\u2010TNHL group (PFS: 60% vs. 30%, <jats:italic>p<\/jats:italic>\u2009=\u2009.075; GRFS: 38% vs. 21%, <jats:italic>p<\/jats:italic>\u2009=\u2009.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acknowledging the retrospective nature of our study, our results indicate that allo\u2010SCT has a curative potential in patients with T\u2010NHL even in refractory status.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.14113","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T05:00:19Z","timestamp":1697518819000},"page":"276-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Allogeneic hematopoetic stem cell transplant for patients with refractory <scp>T\u2010Cell<\/scp> lymphomas"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9275-3840","authenticated-orcid":false,"given":"Radwan","family":"Massoud","sequence":"first","affiliation":[{"name":"Department of Stem Cell Transplantation University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Naim","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Transplantation University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evgeny","family":"Klyuchnikov","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Transplantation University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dietlinde","family":"Janson","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Transplantation 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