{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T08:53:37Z","timestamp":1778489617627,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Patients treated for hematologic malignancies are at higher risk for blood stream infections (BSI) and multidrug\u2010resistant organisms (MDRO) are increasingly involved. Studies showed a significant association between rectal colonization status and a higher risk of subsequent MDRO BSI. The objective of our study was to probe the practice of surveillance cultures in Belgian hematology centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A questionnaire was sent to the 13 hematology centers participating in the acute leukemia board of the Belgian Hematology Society. 21 questions probed for the method of surveillance cultures, MDRO screened, antimicrobial prophylaxis, and empirical therapy and their relationship with colonization status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All centers completed the questionnaire in full. Routine gastrointestinal surveillance cultures in hematologic patients are taken in 10 hospitals. Organisms tested for included mostly ESBL (<jats:italic>n<\/jats:italic>\u2009=\u20099) and carbapenem\u2010resistant (<jats:italic>n<\/jats:italic>\u2009=\u20098) <jats:italic>Enterobacterales<\/jats:italic>. All centers with a screening strategy adapt empiric antibiotic therapy based on MDRO colonization. Prophylaxis strategies are variable, only two centers adapt prophylaxis upon documentation of fluoroquinolone resistance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The majority of the Belgian centers perform routine surveillance cultures and adapt empiric therapy for neutropenic fever accordingly. Other reasons for testing include to gain insight into local epidemiology and to prevent in\u2010hospital transmission. In general, there was significant variability in surveillance dimensions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.14157","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:08:15Z","timestamp":1703117295000},"page":"627-632","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Screening for multidrug\u2010resistant organisms in high\u2010risk hospitalized patients with hematologic diseases"],"prefix":"10.1111","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5853-1616","authenticated-orcid":false,"given":"Valentine","family":"Delanote","sequence":"first","affiliation":[{"name":"AZ Delta internal medicine AZ Delta General Hospital  Roeselare Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3655-8519","authenticated-orcid":false,"given":"Rutger","family":"Callens","sequence":"additional","affiliation":[{"name":"AZ Delta Clinical Hematology AZ Delta General Hospital  Roeselare Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7707-285X","authenticated-orcid":false,"given":"Dirk","family":"Vogelaers","sequence":"additional","affiliation":[{"name":"AZ Delta Infectiology AZ Delta General Hospital  Roeselare Belgium"},{"name":"Faculty of Health sciences University Ghent  Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9599-2142","authenticated-orcid":false,"given":"Dries","family":"Deeren","sequence":"additional","affiliation":[{"name":"AZ Delta Clinical Hematology AZ Delta General Hospital  Roeselare Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.03.004"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2013.12.006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-1093-x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-012-0269-y"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku305"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-018-3341-6"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-021-01753-z"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-022-07154-3"},{"issue":"1","key":"e_1_2_10_11_1","article-title":"Guidance of empirical antimicrobial therapy by surveillance cultures in high\u2010risk neutropenic patients: a retrospective cohort study","volume":"11","author":"Court JR","year":"2022","journal-title":"Antimicrob Resist Infect Control"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-022-00700-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2013.091025"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12859"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2018.02.021"},{"key":"e_1_2_10_16_1","unstructured":"NicolauDP.Current challenges in the management of the infected patient.2011Available from:http:\/\/journals.lww.com\/co-infectiousdiseases"},{"key":"e_1_2_10_17_1","unstructured":"DuysburghE.Surveillance of bloodstream infections in Belgian hospitals; 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