{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:20:59Z","timestamp":1792225259521,"version":"4.4.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Having a haematological condition can adversely affect the quality of life (QoL) of family members\/partners of patients. It is important to measure this often ignored burden in order to implement appropriate supportive interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To measure current impact of haematological conditions on the QoL of family members\/partners of patients, using the Family Reported Outcome Measure\u201016 (FROM\u201016).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study, recruited online through patient support groups, involved UK family members\/partners of people with haematological conditions completing the FROM\u201016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>183 family members\/partners (mean age\u2009=\u200960.5\u2009years, SD\u2009=\u200913.2; females\u2009=\u200962.8%) of patients (mean age\u2009=\u200964.1, SD\u2009=\u200912.8; females\u2009=\u200946.4%) with 12 haematological conditions completed the FROM\u201016. The FROM\u201016 mean total score was 14.0 (SD\u2009=\u20097.2), meaning \u2018a moderate effect on QoL\u2019. The mean FROM\u201016 scores of family members of people with multiple myeloma (mean\u2009=\u200915.8, SD\u2009=\u20096.3, <jats:italic>n<\/jats:italic>\u2009=\u200999) and other haematological malignancies (mean\u2009=\u200913.9, SD\u2009=\u20097.8, <jats:italic>n<\/jats:italic>\u2009=\u200929) were higher than of people with pernicious anaemia (mean\u2009=\u200910.7, SD\u2009=\u20097.5, <jats:italic>n<\/jats:italic>\u2009=\u200947) and other non\u2010malignant conditions (mean\u2009=\u200911, SD\u2009=\u20097.4, n\u2009=\u200956, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). Over one third (36.1%, <jats:italic>n<\/jats:italic>\u2009=\u2009183) of family members experienced a \u2018very large effect\u2019 (FROM\u201016 score&gt;16) on their quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Haematological conditions, in particular those of malignant type, impact the QoL of family members\/partners of patients. Healthcare professionals can now, using FROM\u201016, identify those most affected and should consider how to provide appropriate holistic support within routine practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ejh.14206","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T07:58:10Z","timestamp":1712303890000},"page":"117-126","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Measurement of the major ignored burden of multiple myeloma, pernicious anaemia and of other haematological conditions on partners and family members: A cross\u2010sectional study"],"prefix":"10.1111","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8158-712X","authenticated-orcid":false,"given":"R.","family":"Shah","sequence":"first","affiliation":[{"name":"Division of Infection and Immunity School of Medicine, Cardiff University  Cardiff UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2143-1646","authenticated-orcid":false,"given":"A. 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