{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T06:41:27Z","timestamp":1776580887006,"version":"3.51.2"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006304","name":"Aalborg Universitetshospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006304","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008363","name":"Kr\u00e6ftens bek\u00e6mpelse","doi-asserted-by":"publisher","award":["R327\u2010A18892"],"award-info":[{"award-number":["R327\u2010A18892"]}],"id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Risk of cardiovascular disease (CVD) in patients with classical Hodgkin lymphoma (cHL) undergoing contemporary treatment is unclear. cHL patients\u2009\u2265\u200918\u2009years at diagnosis treated with doxorubicin\u2010containing chemotherapy between 2000 and 2022 were matched 1:5 with comparators on birth year, sex, and Charlson Comorbidity Index at time of matching (score of 0 or\u2009\u2265\u20091). Cause\u2010specific cumulative incidence of a composite of CVDs with corresponding 95% confidence intervals (CIs) were computed with death and lymphoma relapse as competing events (i.e., by censoring individuals at such occurrences) using the Aalen\u2010Johansen estimator. A total of 1905 patients and 9525 comparators with a median follow\u2010up of 10\u2009years (interquartile range, [IQR]: 5.9\u201317.4). Median age was 39\u2009years (IQR: 27\u201356), median cumulative doxorubicin dose was 250\u2009mg\/m\n                    <jats:sup>2<\/jats:sup>\n                    (IQR: 200\u2013300). The CVD cumulative incidences were 4.7% (95% CI: 3.6\u20135.7) for patients versus 2.6% (95% CI: 2.3\u20132.9) for comparators at 5\u2009years, 8.9% (95% CI: 7.2\u201310.5) versus 5.5% (95% CI: 4.9\u20136.0) at 10\u2009years, and 17.0% (95% CI: 14.1\u201319.9) versus 8.2% (95% CI: 7.4\u20139.0) at 15\u2009years. CVD remains a substantial effect after contemporary treatment for cHL, suggesting that awareness of symptoms and a low threshold for referral to diagnostic examination are still important measures during survivorship.\n                  <\/jats:p>","DOI":"10.1111\/ejh.14334","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T03:54:19Z","timestamp":1730865259000},"page":"343-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Risk of Cardiovascular Disease in Patients With Classical Hodgkin Lymphoma: A Danish Nationwide Register\u2010Based Cohort Study"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1049-9285","authenticated-orcid":false,"given":"Sissel J.","family":"Godtfredsen","sequence":"first","affiliation":[{"name":"Department of Cardiology Aalborg University Hospital  Aalborg 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