{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T17:45:46Z","timestamp":1786470346223,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001168","name":"Cancer Council Queensland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001168","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001794","name":"University of Queensland","doi-asserted-by":"publisher","award":["ACCR\u2010118"],"award-info":[{"award-number":["ACCR\u2010118"]}],"id":[{"id":"10.13039\/501100001794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European J of Haematology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine global practices for identifying and managing central venous access device (CVAD) complications\u2014catheter\u2010associated bloodstream infection (CABSI), thrombosis, and occlusion\u2014in paediatric cancer care, comparing patterns between high\u2010 and other\u2010income countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional international survey was conducted from 2022 to 2023 and analysed 2024 to 2025. Clinicians involved in paediatric CVAD cancer care were recruited through global networks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 161 respondents from 38 countries completed the complication section, including 102 (63.4%) from high\u2010income and 59 (36.6%) from other\u2010income countries (lower\u2010 and upper\u2010middle income). For CABSI, blood culture was the main diagnostic method (122 [75.8%]; high\u2010income: 87 [85.3%], other\u2010income: 35 [59.3%]). Differential time to positivity was more often reported in other\u2010income settings (33 [55.9%] vs. 35 [34.3%]), who also more frequently initiated antibiotics based on nonspecific or immediate criteria. CABSI treatment varied, with intravenous antibiotics (68 [60.7%]) and catheter removal (47 [42.0%]) most reported. For thrombosis, anticoagulation before line removal was common (88 [54.7%]), and alteplase use was higher in high\u2010income countries (76 [74.5%] vs. 19 [32.2%]). Thrombolytic agents were the most reported treatment for occlusion (103 [64.0%]), especially in high\u2010income countries (77 [75.5%] vs. 26 [44.1%]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CVAD complication management varies by country income level, highlighting the need for context\u2010adapted guidelines, training, and equitable access to key resources.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ejh.70041","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T04:25:52Z","timestamp":1759206352000},"page":"578-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Complications in Central Venous Access Devices in Paediatric Cancer Care: A Global Cross\u2010Sectional Survey"],"prefix":"10.1111","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3628-0134","authenticated-orcid":false,"given":"Sabrina","family":"de Souza","sequence":"first","affiliation":[{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences The University of Queensland  St Lucia Queensland Australia"},{"name":"Queensland Children's Hospital Children's Health Queensland Hospital and Health Service  South Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1167-9106","authenticated-orcid":false,"given":"Mari D.","family":"Takashima","sequence":"additional","affiliation":[{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences The University of Queensland  St Lucia Queensland Australia"},{"name":"Queensland Children's Hospital Children's Health Queensland Hospital and Health Service  South Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Areum","family":"Hyun","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery Griffith University  Nathan Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Gibson","sequence":"additional","affiliation":[{"name":"School of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences The University of Queensland  St Lucia Queensland Australia"},{"name":"Queensland Children's Hospital Children's Health Queensland Hospital and Health Service  South Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6310-5825","authenticated-orcid":false,"given":"Thiago Lopes","family":"Silva","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nursing Universidade Federal de Santa Catarina  Florianopolis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8347-1363","authenticated-orcid":false,"given":"Patricia Kuerten","family":"Rocha","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Nursing Universidade Federal de Santa Catarina  Florianopolis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriporn","family":"Vetcho","sequence":"additional","affiliation":[{"name":"Faculty of Nursing Prince of Songkla University  Songkhla Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie C. 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