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In 2011, 5\u2010azacitidine became the first funded DMT for MDS and chronic myelomonocytic leukaemia (CMML) patients in Australia and national patient blood management (PBM) guidelines were published.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Describe red blood cell transfusion (RBC\u2010T) and platelet transfusion (PLT\u2010T) burden in MDS\/CMML and any changes since 2011.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Retrospective longitudinal cohort study of all MDS\/CMML patients in the state of Victoria (population 6.5\u2009million) from 2009 to 2022, linking hospital admissions dataset, cancer and death registries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      7043 patients (5715 MDS; 1328 CMML), with median follow\u2010up 1.8\u2009years (interquartile range [IQR]: 0.5\u20134.0\u2009years), had 55\u2009048 RBC\u2010T and 10\u2009749 PLT\u2010T episodes. By 5\u2009years post\u2010diagnosis, patients had on average 14 RBC\u2010T and 3 PLT\u2010T admissions, with transfusion burden affected by MDS subtype. PLT\u2010T were significantly higher post\u20102011 versus pre\u20102011 (0.8 more PLT\u2010T admissions by 2\u2009years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no difference in RBC\u2010T admissions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Since 2011, RBC\u2010T burden has remained stable, but PLT\u2010Ts have increased. Given the potential costs and limited PLT inventories, this impacts blood supply planning and highlights the need for research to optimise PLT\u2010T in MDS\/CMML patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ejh.70233","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:52:01Z","timestamp":1780275121000},"page":"1007-1015","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Changes in Transfusion Practice in Myelodysplastic Syndromes: A Population Data\u2010Linkage Study"],"prefix":"10.1111","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1923-3133","authenticated-orcid":false,"given":"Allison","family":"Mo","sequence":"first","affiliation":[{"name":"Transfusion Research Unit, School of Public Health &amp; Preventive Medicine, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"},{"name":"Monash Haematology, Monash Health  Melbourne Australia"},{"name":"Austin Pathology and Department of Haematology Austin Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le Thi Phuong","family":"Thao","sequence":"additional","affiliation":[{"name":"Transfusion Research Unit, School of Public Health &amp; Preventive Medicine, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Wellard","sequence":"additional","affiliation":[{"name":"Transfusion Research Unit, School of Public Health &amp; Preventive Medicine, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7527-2340","authenticated-orcid":false,"given":"Erica M.","family":"Wood","sequence":"additional","affiliation":[{"name":"Transfusion Research Unit, School of Public Health &amp; Preventive Medicine, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"},{"name":"Monash Haematology, Monash Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3185-6488","authenticated-orcid":false,"given":"Jake","family":"Shortt","sequence":"additional","affiliation":[{"name":"Monash Haematology, Monash Health  Melbourne Australia"},{"name":"Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9698-7185","authenticated-orcid":false,"given":"Zoe K.","family":"McQuilten","sequence":"additional","affiliation":[{"name":"Transfusion Research Unit, School of Public Health &amp; Preventive Medicine, Faculty of Medicine, Nursing &amp; Health Sciences Monash University  Melbourne Australia"},{"name":"Monash Haematology, Monash Health  Melbourne Australia"},{"name":"Department of Haematology Alfred Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,31]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12054"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2022.2156793"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2019.1622700"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16884"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12155"},{"key":"e_1_2_13_7_1","unstructured":"Australian Government Department of Health \u201cAzacitidine Powder for Injection 100mg Vidaza Public Summary Document \u201d(2009) http:\/\/www.pbs.gov.au\/info\/industry\/listing\/elements\/pbac\u2010meetings\/psd\/2009\u201007\/pbac\u2010psd\u2010azacitidine\u2010jul09."},{"key":"e_1_2_13_8_1","volume-title":"Module 3 Medical","author":"National Blood Authority","year":"2012"},{"key":"e_1_2_13_9_1","unstructured":"Australian Bureau of Statistics \u201cSnapshot of Victoria \u201d(2022) https:\/\/www.abs.gov.au\/articles\/snapshot\u2010vic\u2010202."},{"key":"e_1_2_13_10_1","unstructured":"Australian Prudential Regulation Authority (APRA) \u201cQuarterly Private Health Insurance Statistics \u201d(2024) https:\/\/www.apra.gov.au\/quarterly\u2010private\u2010health\u2010insurance\u2010statistics\u20100."},{"key":"e_1_2_13_11_1","volume-title":"The International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification","author":"Australian Insittute of Health and Welfare","year":"2006"},{"key":"e_1_2_13_12_1","unstructured":"National Centre for Classification in Health \u201cThe Australian Classification of Health Interventions (ACHI) \u201d(2006) 5th ed. 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