{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:13:58Z","timestamp":1770740038960,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,8,11]],"date-time":"2013-08-11T00:00:00Z","timestamp":1376179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several studies have already shown that transcranial direct current stimulation (<jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>) is a useful tool for enhancing recovery in aphasia. However, all <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> studies have previously investigated the effects using unihemisperic stimulation. No reports to date have examined the role of bihemispheric <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> on aphasia recovery. Here, eight aphasic persons with apraxia of speech underwent intensive language therapy in two different conditions: real bihemispheric anodic ipsilesional stimulation over the left <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>roca's area and cathodic contralesional stimulation over the right homologue of <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>roca's area, and a sham condition. In both conditions, patients underwent concurrent language therapy for their apraxia of speech. The language treatment lasted 10\u00a0days (Monday to Friday, then weekend off, then Monday to Friday). There was a 14\u2010day intersession interval between the real and the sham conditions. In all patients, language measures were collected before (T0), at the end of (T10) and 1\u00a0week after the end of (F\/U) treatment. Results showed that after simultaneous excitatory stimulation to the left frontal hemisphere and inhibitory stimulation to the right frontal hemisphere regions, patients exhibited a significant recovery not only in terms of better accuracy and speed in articulating the treated stimuli but also in other language tasks (picture description, noun and verb naming, word repetition, word reading) which persisted in the follow\u2010up session. Taken together, these data suggest that bihemispheric anodic ipsilesional and cathodic contralesional stimulation in chronic aphasia patients may affect the treated function, resulting in a positive influence on different language tasks.<\/jats:p>","DOI":"10.1111\/ejn.12332","type":"journal-article","created":{"date-parts":[[2013,8,12]],"date-time":"2013-08-12T04:22:33Z","timestamp":1376281353000},"page":"3370-3377","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia"],"prefix":"10.1111","volume":"38","author":[{"given":"Paola","family":"Marangolo","sequence":"first","affiliation":[{"name":"Facolt\u00e0 di Medicina Universit\u00e0 Politecnica Marche Via Tronto 10A 60020 Ancona Italy"},{"name":"IRCCS Fondazione Santa Lucia Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Fiori","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna","family":"Cipollari","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serena","family":"Campana","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelina","family":"Razzano","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Di Paola","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"},{"name":"Dipartimento di Medicina Interna e Sanit\u00e0 Pubblica Universit\u00e0 dell'Aquila L'Aquila Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Koch","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"},{"name":"Universit\u00e0 di Tor Vergata Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Caltagirone","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Santa Lucia Roma Italy"},{"name":"Universit\u00e0 di Tor Vergata Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.576785"},{"key":"e_1_2_8_3_1","volume-title":"Esame del Linguaggio (II versione)","author":"Ciurli P.","year":"1996"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-9452(78)80006-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-9452(66)80028-X"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)64855-6"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/384159a0"},{"key":"e_1_2_8_8_1","volume-title":"Motor Speech Disorders: Substrates, Differential Diagnosis, and Management","author":"Duffy J.R.","year":"2005"},{"key":"e_1_2_8_9_1","unstructured":"Fanzago F.(1983).Test di valutazione dell'articolazione. 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