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However, it is not known whether <jats:styled-content style=\"fixed-case\">MVF<\/jats:styled-content> training influences the hemispheric balance between the M1s. This topic is of extreme relevance when <jats:styled-content style=\"fixed-case\">MVF<\/jats:styled-content> training is applied to stroke rehabilitation, as the competitive interaction between the two hemispheres induces abnormal interhemispheric inhibition (<jats:styled-content style=\"fixed-case\">IHI<\/jats:styled-content>) that weakens motor function in stroke patients. In the present study, we evaluated, in a group of healthy subjects, the effect of motor training and <jats:styled-content style=\"fixed-case\">MVF<\/jats:styled-content> training on the excitability of the two M1s and the <jats:styled-content style=\"fixed-case\">IHI<\/jats:styled-content> between M1s. The <jats:styled-content style=\"fixed-case\">IHI<\/jats:styled-content> from the \u2018active\u2019 M1 to the opposite M1 (where \u2018active\u2019 means the M1 contralateral to the moving hand in the motor training and the M1 of the seen hand in the <jats:styled-content style=\"fixed-case\">MVF<\/jats:styled-content> training) increased, after training, in both the experimental conditions. Only after motor training did we observe an increase in the excitability of the active M1. Our findings show that training based on <jats:styled-content style=\"fixed-case\">MVF<\/jats:styled-content> may influence the excitability of the transcallosal pathway and support its use in disorders where abnormal <jats:styled-content style=\"fixed-case\">IHI<\/jats:styled-content> is a potential target, such as stroke, where an imbalance between the affected and unaffected M1s has been documented.<\/jats:p>","DOI":"10.1111\/ejn.12615","type":"journal-article","created":{"date-parts":[[2014,5,13]],"date-time":"2014-05-13T04:45:06Z","timestamp":1399956306000},"page":"2581-2588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Training based on mirror visual feedback influences transcallosal communication"],"prefix":"10.1111","volume":"40","author":[{"given":"Laura","family":"Avanzino","sequence":"first","affiliation":[{"name":"Department of Experimental Medicine Section of Human Physiology and Centro Polifunzionale di Scienze Motorie University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Raffo","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Pelosin","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Ogliastro","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Marchese","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piero","family":"Ruggeri","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine Section of Human Physiology and Centro Polifunzionale di Scienze Motorie University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Abbruzzese","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health University of Genoa Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.134510"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2008.06086.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.90428.2008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.09.036"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4893-10.2011"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bht139"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4076-07.2008"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-980X(98)00013-7"},{"key":"e_1_2_7_10_1","article-title":"Mirror movements in movement disorders: a review","volume":"2","author":"Cox B.C.","year":"2012","journal-title":"Tremor. 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