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These two roles of mentation and reflexive response recruit the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> nodes and other task networks differently. Existing research has revealed that the interactions inside the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> (between nodes within the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content>) and outside the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> (between nodes in the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> and nodes in task networks) have different modes, in terms of both strength and timing. These findings raise interesting questions. For example, are the internal and external interactions of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> equally linear or nonlinear? This study examined these interaction patterns using datasets from the Human Connectome Project. A maximal information\u2010based nonparametric exploration statistics strategy was utilized to characterize the full correlations, and the Pearson correlation was used to capture the linear component of the full correlations. We then contrasted the level of linearity\/nonlinearity with respect to the internal and external interactions of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content>. After a brain\u2010wide exploration, we found that the interactions between the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> and the sensorimotor\u2010related networks (including the sensorimotor, sensory association, and integration areas) showed more nonlinearity, whereas those between the intra\u2010<jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content> nodes were similarly less nonlinear. These findings may provide a clue for understanding the underlying neuronal principles of the internal and external roles of the <jats:styled-content style=\"fixed-case\">DMN<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/ejn.13112","type":"journal-article","created":{"date-parts":[[2015,10,23]],"date-time":"2015-10-23T16:48:42Z","timestamp":1445618922000},"page":"78-88","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Different interaction modes for the default mode network revealed by resting state functional magnetic resonance imaging"],"prefix":"10.1111","volume":"43","author":[{"given":"Nianming","family":"Zuo","sequence":"first","affiliation":[{"name":"Brainnetome Center Institute of Automation, Chinese Academy of Sciences Beijing China"},{"name":"National Laboratory of Pattern Recognition Institute of Automation, Chinese Academy of Sciences Beijing 100190 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