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Decline in auditory perception provokes deficits in the ability to localize sound sources and reduces speech perception, particularly in noise. In addition to a loss of peripheral hearing sensitivity, changes in more complex central structures have also been demonstrated. Related to these, this study examines the auditory directional maps in the deep layers of the superior colliculus of the rat. Hence, anesthetized Sprague\u2013Dawley adult (10\u00a0months) and aged (22\u00a0months) rats underwent distortion product of otoacoustic emissions (<jats:styled-content style=\"fixed-case\">DPOAE<\/jats:styled-content>s) to assess cochlear function. Then, auditory brainstem responses (<jats:styled-content style=\"fixed-case\">ABR<\/jats:styled-content>s) were assessed, followed by extracellular single\u2010unit recordings to determine age\u2010related effects on central auditory functions. <jats:styled-content style=\"fixed-case\">DPOAE<\/jats:styled-content> amplitude levels were decreased in aged rats although they were still present between 3.0 and 24.0 <jats:styled-content style=\"fixed-case\">kH<\/jats:styled-content>z. <jats:styled-content style=\"fixed-case\">ABR<\/jats:styled-content> level thresholds in aged rats were significantly elevated at an early (cochlear nucleus \u2013 wave <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>) stage in the auditory brainstem. In the superior colliculus, thresholds were increased and the tuning widths of the directional receptive fields were significantly wider. Moreover, no systematic directional spatial arrangement was present among the neurons of the aged rats, implying that the topographical organization of the auditory directional map was abolished. These results suggest that the deterioration of the auditory directional spatial map can, to some extent, be attributable to age\u2010related dysfunction at more central, perceptual stages of auditory processing.<\/jats:p>","DOI":"10.1111\/ejn.13302","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T08:39:04Z","timestamp":1466066344000},"page":"2084-2094","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of aging on peripheral and central auditory processing in rats"],"prefix":"10.1111","volume":"44","author":[{"given":"Margarida","family":"Costa","sequence":"first","affiliation":[{"name":"Centre de Recherche en Neuropsychologie et Cognition Universit\u00e9 de Montr\u00e9al C.P. 6128, Succ. 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