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In the auditory system, strong enhancement of binaural information takes place between the brainstem and the midbrain; however, the underlying cellular mechanisms are unknown. Here we investigated the transformation of binaural information in the dorsal nucleus of the lateral lemniscus (\n                    <jats:styled-content style=\"fixed-case\">DNLL<\/jats:styled-content>\n                    ), a nucleus that connects the binaural nuclei in the brainstem and the inferior colliculus in the midbrain. We used\n                    <jats:italic>in\u00a0vitro<\/jats:italic>\n                    and\n                    <jats:italic>in\u00a0vivo<\/jats:italic>\n                    electrophysiology in adult Mongolian gerbils to show that\n                    <jats:italic>N<\/jats:italic>\n                    \u2010methyl\u2010\n                    <jats:italic>D<\/jats:italic>\n                    \u2010aspartate receptor (\n                    <jats:styled-content style=\"fixed-case\">NMDAR<\/jats:styled-content>\n                    s) play a critical role in neuronal encoding of stimulus properties in the\n                    <jats:styled-content style=\"fixed-case\">DNLL<\/jats:styled-content>\n                    . While\n                    <jats:styled-content style=\"fixed-case\">NMDAR<\/jats:styled-content>\n                    s increase firing rates, the timing and the accuracy of the neuronal responses remain unchanged.\n                    <jats:styled-content style=\"fixed-case\">NMDAR<\/jats:styled-content>\n                    \u2010mediated excitation increases the information about the acoustic stimulus. Taken together, our results show that\n                    <jats:styled-content style=\"fixed-case\">NMDAR<\/jats:styled-content>\n                    s in the\n                    <jats:styled-content style=\"fixed-case\">DNLL<\/jats:styled-content>\n                    enhance the auditory information content in adult mammal brainstem.\n                  <\/jats:p>","DOI":"10.1111\/ejn.13859","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T02:37:16Z","timestamp":1517884636000},"page":"858-865","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Electrogenic\n                    <i>N<\/i>\n                    \u2010methyl\u2010\n                    <i>D<\/i>\n                    \u2010aspartate receptor signaling enhances binaural responses in the adult brainstem"],"prefix":"10.1111","volume":"47","author":[{"given":"Ida","family":"Siveke","sequence":"first","affiliation":[{"name":"Division of Neurobiology Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"},{"name":"Institute of Zoology and Neurobiology Ruhr\u2010Universit\u00e4t Bochum 44780 Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian J.","family":"Ammer","sequence":"additional","affiliation":[{"name":"Division of Neurobiology Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"},{"name":"Centre for Integrative Physiology Edinburgh Medical School: Biomedical Sciences University of Edinburgh Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Gleiss","sequence":"additional","affiliation":[{"name":"Division of Neurobiology Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"},{"name":"Graduate School for Systemic Neurosciences Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Grothe","sequence":"additional","affiliation":[{"name":"Division of Neurobiology Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"},{"name":"Graduate School for Systemic Neurosciences Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Leibold","sequence":"additional","affiliation":[{"name":"Computational Neuroscience Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0957-4241","authenticated-orcid":false,"given":"Felix","family":"Felmy","sequence":"additional","affiliation":[{"name":"Division of Neurobiology Department Biology II Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen Planegg\u2010Martinsried Germany"},{"name":"Institute of Zoology University of Veterinary Medicine Hannover 30599 Hannover 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