{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:56Z","timestamp":1787014136810,"version":"build-2736575974"},"reference-count":48,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T00:00:00Z","timestamp":1520553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Copenhagen Excellence Programme for Interdisciplinary Research"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The functional relevance of cortical reorganization post\u2010stroke is still not well understood. In this study, we investigated task\u2010specific modulation of cortical connectivity between neural oscillations in key motor regions during the early phase after stroke.\n                    <jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">EMG<\/jats:styled-content>\n                    recordings were examined from 15 patients and 18 controls during a precision grip task using the affected hand. Each patient attended two sessions in the acute and subacute phase (median of 3 and 34\u00a0days) post\u2010stroke. Dynamic causal modelling (\n                    <jats:styled-content style=\"fixed-case\">DCM<\/jats:styled-content>\n                    ) for induced responses was used to investigate task\u2010specific modulations of oscillatory couplings in a bilateral network comprising supplementary motor area (\n                    <jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>\n                    ), dorsal premotor cortex (\n                    <jats:styled-content style=\"fixed-case\">PM<\/jats:styled-content>\n                    d) and primary motor cortex (M1). Fourteen models were constructed for each subject, and the input induced by the experimental manipulation (task) was set to inferior parietal lobule (\n                    <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content>\n                    ). Bayesian model selection favoured a fully connected model. A reduced coupling from\n                    <jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>\n                    and intact M1 in the \u03b3\u2010band (31\u201348\u00a0Hz) to lesioned M1 in the \u03b2\u2010band (15\u201330\u00a0Hz) was observed in patients in the acute phase compared to controls. Behavioural performance improved significantly in the subacute phase, while an increased positive coupling from intact\n                    <jats:styled-content style=\"fixed-case\">PM<\/jats:styled-content>\n                    d to lesioned M1 and a less negative modulation from lesioned M1 to intact M1 were observed for patients compared to controls both from the \u03b3\u2010band to the \u03b2\u2010band. We infer that the observed differences in cross\u2010frequency cortical interactions are important for functional recovery.\n                  <\/jats:p>","DOI":"10.1111\/ejn.13874","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T15:37:43Z","timestamp":1519227463000},"page":"1024-1032","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Modulation of task\u2010related cortical connectivity in the acute and subacute phase after stroke"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1876-9876","authenticated-orcid":false,"given":"Lisbeth H.","family":"Larsen","sequence":"first","affiliation":[{"name":"CopenRehab Department of Public Health University of Copenhagen Copenhagen Denmark"},{"name":"Department for Neuroscience Panum Institute University of Copenhagen Blegdamsvej 3 2200 Copenhagen 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