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Previously, pathological gambling (<jats:styled-content style=\"fixed-case\">PG<\/jats:styled-content>) and Parkinson's disease (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) have been associated with differential arousal levels during gambling behavior. However, no research considered the specific autonomic responses of Parkinson's disease patients with pathological gambling and with a previous history of gambling. Thus, this study investigated skin conductance responses (<jats:styled-content style=\"fixed-case\">SCR<\/jats:styled-content>s), skin conductance level (<jats:styled-content style=\"fixed-case\">SCL<\/jats:styled-content>) and heart rate (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) during the Iowa Gambling Task (<jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content>) in two groups of <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients with gambling disorder, active (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> Gamblers; <jats:italic>n<\/jats:italic>\u00a0=\u00a014) or remitted (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> Non\u2010Gamblers; <jats:italic>n<\/jats:italic>\u00a0=\u00a013) and a control group of patients with Parkinson's disease only (<jats:italic>n<\/jats:italic>\u00a0=\u00a013). Anticipatory autonomic responses to disadvantageous decks and advantageous decks during the Iowa Gambling Task were measured for each participant. The <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> Gamblers group performed worse than the <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> Non\u2010Gamblers and the control groups at the <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content> task and exhibited lower <jats:styled-content style=\"fixed-case\">SCR<\/jats:styled-content>s, <jats:styled-content style=\"fixed-case\">SCL<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> during the decision\u2010making processing of cards belonging to disadvantageous decks. The role of autonomic and behavioral measures was considered.<\/jats:p>","DOI":"10.1111\/ejn.13993","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T08:30:41Z","timestamp":1528705841000},"page":"2392-2400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Pathological Gambling in Parkinson's disease: Autonomic measures supporting impaired decision\u2010making"],"prefix":"10.1111","volume":"50","author":[{"given":"Laura","family":"Angioletti","sequence":"first","affiliation":[{"name":"Department of Psychology Catholic University of the Sacred Heart Milan Italy"},{"name":"Research Unit in Affective and Social Neuroscience Catholic University of the Sacred Heart Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9199-4084","authenticated-orcid":false,"given":"Chiara","family":"Siri","sequence":"additional","affiliation":[{"name":"Parkinson Institute ASST G. 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