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Here, written before he died, Ray Guillery chronicles his discovery of the aberrant circuitry from eye to brain in the Siamese cat. Ray's characterization of visual pathway anomalies in this temperature sensitive mutation of tyrosinase and thus melanin synthesis in domestic cats opened the exploration of albinism and simultaneously, a genetic approach to the organization of neural circuitry. I follow this account with a remembrance of Ray's influence on my work. Beginning with my postdoc research with Ray on the cat visual pathway, through my own work on the mechanisms of retinal axon guidance in the developing mouse, Ray and I had a continuous and rich dialogue about the albino visual pathway. I will present the questions Ray posed and clues we have to date on the still\u2010elusive link between eye pigment and the proper balance of ipsilateral and contralateral retinal ganglion cell projections to the brain.<\/jats:p>","DOI":"10.1111\/ejn.14396","type":"journal-article","created":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T04:38:59Z","timestamp":1551155939000},"page":"913-927","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Conversations with Ray Guillery on albinism: linking Siamese cat visual pathway connectivity to mouse retinal development"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6253-505X","authenticated-orcid":false,"given":"Carol","family":"Mason","sequence":"first","affiliation":[{"name":"Departments of Pathology and Cell Biology, Neuroscience, and Ophthalmology Mortimer B. Zuckerman Mind Brain Behavior Institute Columbia University Jerome L. Greene Science Center 3227 Broadway, Room L3\u2010043, Quad 3C New York NY 10027 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Guillery","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Cell Biology, Neuroscience, and Ophthalmology Mortimer B. Zuckerman Mind Brain Behavior Institute Columbia University Jerome L. 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