{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:08:06Z","timestamp":1789826886707,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T00:00:00Z","timestamp":1607299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T00:00:00Z","timestamp":1607299200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Interest in transcranial direct current stimulation (tDCS) to alter cortical excitability, facilitate neural plasticity, and improve performance is increasing. Subjects often report temporary stimulation\u2010related sensations, which might distract from the task being performed or compromise blinding. tDCS is also prone to high outcome irregularity and one potential variability source is the biological sex of the subject. The purpose of this study was to re\u2010analyze existing tolerability data to ascertain any sex differences in sensation severity and blinding guesses from tDCS at 2 mA and 4\u00a0mA. Each subject underwent tDCS at three randomly ordered intensities (sham, 2\u00a0mA, 4\u00a0mA), reported the severity sensations experienced, and guessed which tDCS condition they underwent (blinding). Women reported higher sensation severities than men from 2 mA and 4\u00a0mA tDCS and higher severities with increasing intensity (sham\u00a0&lt;\u00a02\u00a0mA\u00a0&lt;\u00a04\u00a0mA). Men reported similar severities in all stimulation conditions. Both sexes distinguished sham from 2 mA and 4\u00a0mA, and neither were able to discriminate between 2 mA from 4\u00a0mA. This study highlights differences in severity reports between women and men and adds to the growing body of literature, indicating that current sham methodologies might be inadequate to maintain blinding.<\/jats:p>","DOI":"10.1111\/ejn.15070","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T18:41:20Z","timestamp":1606848080000},"page":"2696-2702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Women report more severe sensations from 2 mA and 4\u00a0mA transcranial direct current stimulation than men"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8360-0199","authenticated-orcid":false,"given":"Craig D.","family":"Workman","sequence":"first","affiliation":[{"name":"Department of Health and Human Physiology University of Iowa Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra 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