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Despite the significant clinical characterization of motor phenotypes, little is known about how electrophysiological data, particularly subthalamic nucleus local field potentials (STN\u2010LFP), differ between TD and PIGD patients. This is relevant since increased STN\u2010LFP bandpower at \u03b1\u2013\u03b2 range (8\u201335\u00a0Hz) is considered a potential PD biomarker and, therefore, a critical setpoint to drive adaptive deep brain stimulation. Acknowledging STN\u2010LFP differences between phenotypes, mainly in rest and movement states, would better fit DBS to clinical and motor demands. We studied this issue through spectral analyses on 35 STN\u2010LFP in TD and PIGD patients during rest and movement. We demonstrated that higher \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    activity (22\u201335\u00a0Hz) was observed in PIGD only during rest. Additionally, bandpower differences between rest and movement occurred at the \u03b1\u2013\u03b2 range, but with different patterns as per phenotypes: movement\u2010induced desynchronization concerned lower frequencies in TD (10\u201320\u00a0Hz) and higher frequencies in PIGD patients (21\u201328\u00a0Hz). Finally, when supervised learning algorithms were employed aiming to discriminate PD phenotypes based on STN\u2010LFP bandpower features, movement information had improved the classification accuracy, achieving peak performances when TD and PIGD movement\u2010induced desynchronization ranges were considered. These results suggest that STN\u2010LFP \u03b2\u2010band encodes phenotype\u2010movement dependent information in PD patients.\n                  <\/jats:p>","DOI":"10.1111\/ejn.15103","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T04:25:45Z","timestamp":1609734345000},"page":"2804-2818","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Spectral characteristics of subthalamic nucleus local field potentials in Parkinson's disease: Phenotype and movement matter"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7100-4303","authenticated-orcid":false,"given":"Fabio","family":"Godinho","sequence":"first","affiliation":[{"name":"Center of Engineering, Modeling and Applied Social Sciences Federal University of ABC S\u00e3o Bernardo do Campo Brazil"},{"name":"Department of Functional Neurosurgery Santa Marcelina Hospital S\u00e3o Paulo 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